(Q82824439)

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Application of partial-filling capillary electrophoresis using lectins and glycosidases for the characterization of oligosaccharides in a therapeutic antibody

scientific article published on 01 November 2011

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Europe PubMed Central

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17 January 2020

Application of partial-filling capillary electrophoresis using lectins and glycosidases for the characterization of oligosaccharides in a therapeutic antibody (English)

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Europe PubMed Central

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17 January 2020

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Yuki Yagi

1

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17 January 2020

Sachio Yamamoto

2

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17 January 2020

Kazuaki Kakehi

3

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17 January 2020

Takao Hayakawa

4

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17 January 2020

Yukihito Ohyama

5

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17 January 2020

Shigeo Suzuki

6

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17 January 2020

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1 November 2011

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17 January 2020

Electrophoresis

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17 January 2020

32

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17 January 2020

21

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17 January 2020

2979-2985

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17 January 2020

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Glycosylation as a strategy to improve antibody-based therapeutics

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Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

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The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

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Analysis of carbohydrates on IgG preparations

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Development of a high performance anion exchange chromatography analysis for mapping of oligosaccharides

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Analysis of N-glycans from recombinant immunoglobulin G by on-line reversed-phase high-performance liquid chromatography/mass spectrometry

1 reference

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7 January 2021

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High-throughput immunoglobulin G N-glycan characterization using rapid resolution reverse-phase chromatography tandem mass spectrometry

1 reference

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7 January 2021

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HILIC analysis of fluorescence-labeled N-glycans from recombinant biopharmaceuticals

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Rapid characterization of N-linked glycans from secreted and gel-purified monoclonal antibodies using MALDI-ToF mass spectrometry.

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Carbohydrate analysis of a chimeric recombinant monoclonal antibody by capillary electrophoresis with laser-induced fluorescence detection

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7 January 2021

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On-line CE-LIF-MS technology for the direct characterization of N-linked glycans from therapeutic antibodies

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7 January 2021

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Evaluation of oligosaccharide methods for carbohydrate analysis in a fully human monoclonal antibody and comparison of the results to the monosaccharide composition determination by a novel calculation

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Separation of 1-aminopyrene-3,6,8-trisulfonate-labeled asparagine-linked fetuin glycans by capillary gel electrophoresis

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7 January 2021

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Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics

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Evaluation of association constants between drug enantiomers and human alpha 1-acid glycoprotein by applying a partial-filling technique in affinity capillary electrophoresis.

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Use of a partial-filling technique in affinity capillary electrophoresis for determining binding constants of ligands to receptors

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On-column ligand synthesis coupled to partial-filling affinity capillary electrophoresis to estimate binding constants of ligands to a receptor

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Flow-through partial-filling affinity capillary electrophoresis can estimate binding constants of neutral ligands to receptors via a competitive assay technique

1 reference

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7 January 2021

based on heuristic

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Partial-filling affinity capillary electrophoresis

1 reference

https://api.crossref.org/works/10.1002%2FELPS.201100126

7 January 2021

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Determination of protein-ligand affinity constants from direct migration time in capillary electrophoresis

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https://api.crossref.org/works/10.1002%2FELPS.201100126

7 January 2021

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Lectin affinity capillary electrophoresis in glycoform analysis applying the partial filling technique

1 reference

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7 January 2021

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On-column synthesis coupled to affinity capillary electrophoresis for the determination of binding constants of peptides to glycopeptide antibiotics

1 reference

https://api.crossref.org/works/10.1002%2FELPS.201100126

7 January 2021

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Partial filling multiple injection affinity capillary electrophoresis (PFMIACE) to estimate binding constants of receptors to ligands

1 reference

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Capillary affinity electrophoresis for the screening of post-translational modification of proteins with carbohydrates

1 reference

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7 January 2021

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Capillary electrophoresis with laser-induced fluorescence detection for detailed studies on N-linked oligosaccharide profile of therapeutic recombinant monoclonal antibodies

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7 January 2021

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Use of capillary affinity electrophoresis for the determination of lectin-sugar interactions

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Development of a simple and rapid method for producing non-fucosylated oligomannose containing antibodies with increased effector function

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Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

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In vivo trafficking and catabolism of IgG1 antibodies with Fc associated carbohydrates of differing structure

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Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice

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Identifiers

10.1002/ELPS.201100126

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22145163%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22145163%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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