(Q83134914)

English

Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome

scientific article published on 21 December 2010

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

trans-3-hydroxycotinine

1 reference

ChEBI release 2020-05-28

0 references

1 reference

based on heuristic

inferred from title

mass spectrometry

0 references

0 references

liquid chromatography-tandem mass spectrometry

1 reference

based on heuristic

inferred from title

author name string

Peyton Jacob

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Lisa Yu

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Minjiang Duan

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Lita Ramos

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Olivia Yturralde

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Neal L Benowitz

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

21 December 2010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

879

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

3-4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

267-276

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

describes a project that uses

liquid chromatography-tandem mass spectrometry

1 reference

based on heuristic

inferred from title

Automated homogeneous immunoassay analysis of cotinine in urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioanalytical method validation--a revisit with a decade of progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hair as a biomarker for exposure to tobacco smoke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of nicotine and eight nicotine metabolites in urine of smokers using liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2A6 genetic variation and potential consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toenail nicotine levels as a biomarker of tobacco smoke exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measuring nicotine intake in population surveys: comparability of saliva cotinine and plasma cotinine estimates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast LC/MS in the analysis of small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionization enhancement in atmospheric pressure chemical ionization and suppression in electrospray ionization between target drugs and stable-isotope-labeled internal standards in quantitative liquid chromatography/tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of ion suppression effects in electrospray ionization from mobile phase additives and solid-phase extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tobacco smoke and involuntary smoking

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The determination of nicotine in biological fluids at picogram levels by selected ion recording

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved gas chromatographic method for the determination of nicotine and cotinine in biologic fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of tests used to distinguish smokers from nonsmokers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-performance liquid-chromatographic method for routine simultaneous determination of nicotine and cotinine in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotinine determination by immunoassays may be influenced by other nicotine metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of (3'R,5'S)-trans-3'-hydroxycotinine, a major metabolite of nicotine. Metabolic formation of 3'-hydroxycotinine in humans is highly stereoselective

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-d2 in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the nicotine metabolite trans-3'-hydroxycotinine in urine of smokers using gas chromatography with nitrogen-selective detection or selected ion monitoring

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure of the US population to environmental tobacco smoke: the Third National Health and Nutrition Examination Survey, 1988 to 1991.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interference of nicotine metabolites in cotinine determination by RIA

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cotinine as a biomarker of environmental tobacco smoke exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saliva cotinine levels as a function of collection method

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and validation of sensitive method for determination of serum cotinine in smokers and nonsmokers by liquid chromatography/atmospheric pressure ionization tandem mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new gas chromatography-mass spectrometry method for simultaneous determination of total and free trans-3'-hydroxycotinine and cotinine in the urine of subjects receiving transdermal nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation of an assay for the determination of cotinine and 3-hydroxycotinine in human saliva using automated solid-phase extraction and liquid chromatography with tandem mass spectrometric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and disposition kinetics of nicotine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-analyte procedures for screening for and quantification of drugs in blood, plasma, or serum by liquid chromatography-single stage or tandem mass spectrometry (LC-MS or LC-MS/MS) relevant to clinical and forensic toxicology

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Validation and application of a method for the determination of nicotine and five major metabolites in smokers' urine by solid-phase extraction and liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Directly measured secondhand smoke exposure and COPD health outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous and sensitive measurement of nicotine and cotinine in small amounts of human hair using liquid chromatography/tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of the rate of nicotine metabolism and effects on smoking behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of phenolic metabolites of polycyclic aromatic hydrocarbons in human urine as their pentafluorobenzyl ether derivatives using liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar exposure to a tobacco-specific carcinogen in smokeless tobacco users and cigarette smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondhand smoke exposure in Mexican discotheques

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous and sensitive measurement of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interlaboratory comparability of serum cotinine measurements at smoker and nonsmoker concentration levels: a round-robin study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel validated procedure for the determination of nicotine, eight nicotine metabolites and two minor tobacco alkaloids in human plasma or urine by solid-phase extraction coupled with liquid chromatography-electrospray ionization-tandem mass spect

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of liquid separation techniques to the determination of the main urinary nicotine metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of serum and salivary cotinine measurements by a sensitive high-performance liquid chromatography-tandem mass spectrometry method as an indicator of exposure to tobacco smoke among smokers and nonsmokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms of cytochrome P450 2A6 in a case-control study on lung cancer in a French population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans-3'-hydroxycotinine: disposition kinetics, effects and plasma levels during cigarette smoking

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of long PCR to confirm three common alleles at the CYP2A6 locus and the relationship between genotype and smoking habit

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21208832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JCHROMB.2010.12.012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21208832%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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