(Q83248341)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Total synthesis of (-)-spirangien A, an antimitotic polyketide isolated from the myxobacterium Sorangium cellulosum (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

15-Hydroxy-16-[11-hydroxy-2-(3-hydroxy-4,6-dimethyloct-6-en-2-yl)-4-methoxy-3,9-dimethyl-1,7-dioxaspiro[5.5]undecan-8-yl]-3-methoxy-14-methylheptadeca-4,6,8,10,12-pentaenoic acid

1 reference

Ian Paterson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Alison D Findlay

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Christian Noti

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

1 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

Chemistry - An Asian Journal

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

4

1 reference

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20 January 2020

page(s)

594-611

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

A Combinatorial Approach to Polyketide-Type Libraries by Iterative Asymmetric Aldol Reactions Performed on Solid Support We thank the European Commission (TMR Network ERB-FMR XCT 96-0011 and IHP Network HPRN-CT-2000-00014), EPSRC, Pfizer, and Merck

20 January 2020

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Large rate accelerations in the stille reaction with tri-2-furylphosphine and triphenylarsine as palladium ligands: mechanistic and synthetic implications

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Synthesis of the putative structure of tridachiahydropyrone

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Studies Towards the Total Synthesis of the Marine-Derived Immunosuppressant Discodermolide: Stereoselective Synthesis of a C9-C24 Subunit

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Myxobacterial natural product assembly lines: fascinating examples of curious biochemistry.

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Chemistry. The renaissance of natural products as drug candidates

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Synthesis of 35-deoxy amphotericin B methyl ester: a strategy for molecular editing

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Total synthesis of (-)-reidispongiolide A, an actin-targeting macrolide isolated from the marine sponge Reidispongia coerulea.

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Aldol reactions in polypropionate synthesis: High π-face selectivity of enol borinates from α-chiral methyl and ethyl ketones under substrate control

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Total synthesis of (-)-spirangien A and its methyl ester

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Natural products to drugs: natural product derived compounds in clinical trials

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Pseudoephedrine as a Practical Chiral Auxiliary for the Synthesis of Highly Enantiomerically Enriched Carboxylic Acids, Alcohols, Aldehydes, and Ketones

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9 March 2024

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Spirangien A and B, Highly Cytotoxic and Antifungal Spiroketals from the MyxobacteriumSorangium cellulosum: Isolation, Structure Elucidation and Chemical Modifications

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Readily accessible 12-I-5 oxidant for the conversion of primary and secondary alcohols to aldehydes and ketones

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9 March 2024

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Total synthesis of 2'-O-methylmyxalamide D and (6E)-2'-O-methylmyxalamide D

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Chemistry of Bis-Spiroacetal Systems: Natural Products, Synthesis and Stereochemistry

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9 March 2024

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Total synthesis of spirastrellolide A methyl ester--part 2: Subunit union and completion of the synthesis

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9 March 2024

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Total synthesis of spirastrellolide A methyl ester--part 1: Synthesis of an advanced C17-C40 bis-spiroacetal subunit

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9 March 2024

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Natural products as sources of new drugs over the last 25 years

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9 March 2024

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Spiroketal polyketide formation in Sorangium: identification and analysis of the biosynthetic gene cluster for the highly cytotoxic spirangienes.

1 reference

9 March 2024

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Synthesis of an advanced C10-C32 spiroacetal fragment and assignment of the absolute configuration of spirangien A

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9 March 2024

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Nonanomeric spiroketals in natural products: structures, sources, and synthetic strategies

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9 March 2024

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The modified Julia olefination: alkene synthesis via the condensation of metallated heteroarylalkylsulfones with carbonyl compounds

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Samarium-catalyzed intramolecular Tishchenko reduction of .beta.-hydroxy ketones. A stereoselective approach to the synthesis of differentiated anti 1,3-diol monoesters

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9 March 2024

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Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones

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9 March 2024

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The Palladium-Catalyzed Cross-Coupling Reactions of Organotin Reagents with Organic Electrophiles[New Synthetic Methods(58)]

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9 March 2024

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Antibiotics from Gliding Bacteria, LIV. Isolation and Structure Elucidation of Soraphen A1α, a Novel Antifungal Macrolide fromSorangium cellulosum

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COCI

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Synthesis of the C10-C32 core structure of spirangien A

9 March 2024

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9 March 2024

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Complete genome sequence of the myxobacterium Sorangium cellulosum

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9 March 2024

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The role of natural product chemistry in drug discovery

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The evolving role of natural products in drug discovery

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1,5-anti stereocontrol in the boron-mediated aldol reactions of beta-alkoxy methyl ketones: the role of the formyl hydrogen bond

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Total synthesis of the potent microtubule-stabilizing agent (+)-discodermolide

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9 March 2024

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Understanding the Origins of Remote Asymmetric Induction in the Boron Aldol Reactions of β-Alkoxy Methyl Ketones

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9 March 2024

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Stereoselective syntheses of dihydroxerulin and xerulinic acid, anti-hypocholesterolemic dyes from the fungus Xerula melanotricha

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9 March 2024

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High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoids

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9 March 2024

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Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral

1 reference

9 March 2024

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Identifiers

DOI

10.1002/ASIA.200800445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19173216%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference