(Q83556143)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383712%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Gene therapy for heart failure (English)

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24 January 2020

3

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24 January 2020

author name string

Lisa Tilemann

series ordinal

1

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24 January 2020

Kiyotake Ishikawa

series ordinal

2

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24 January 2020

Roger J Hajjar

series ordinal

4

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24 January 2020

language of work or name

English

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publication date

1 March 2012

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24 January 2020

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24 January 2020

volume

110

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24 January 2020

issue

5

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24 January 2020

page(s)

777-793

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Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors.

24 January 2020

cites work

1 reference

12 December 2020

Gene delivery to airway epithelial cells in vivo: a direct comparison of apical and basolateral transduction strategies using pseudotyped lentivirus vectors

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12 December 2020

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice

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12 December 2020

Cardiac gene delivery with cardiopulmonary bypass

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12 December 2020

Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation.

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12 December 2020

A preclinical animal model to assess the effect of pre-existing immunity on AAV-mediated gene transfer

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

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12 December 2020

Coronary venous retroinfusion of procainamide: a new approach for the management of spontaneous and inducible sustained ventricular tachycardia during myocardial infarction

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12 December 2020

Intramuscular delivery of rAAV-mediated kallikrein gene reduces hypertension and prevents cardiovascular injuries in model rats

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12 December 2020

Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors

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12 December 2020

Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors

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12 December 2020

Targeting phospholamban by gene transfer in human heart failure

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12 December 2020

Cardiac-specific gene expression facilitated by an enhanced myosin light chain promoter

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12 December 2020

Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy

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12 December 2020

In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

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12 December 2020

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance

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12 December 2020

Transendocardial delivery of AAV6 results in highly efficient and global cardiac gene transfer in rhesus macaques

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12 December 2020

Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat.

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12 December 2020

Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle

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A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

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12 December 2020

Genetic manipulation of myocardial beta-adrenergic receptor activation and desensitization

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12 December 2020

Cardiac progenitor cell cycling stimulated by pim-1 kinase

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12 December 2020

Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction

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12 December 2020

Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses.

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12 December 2020

Intrapericardial administration of adenovirus for gene transfer

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12 December 2020

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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12 December 2020

Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice

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12 December 2020

Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B.

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12 December 2020

Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium

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12 December 2020

Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure

1 reference

12 December 2020

Endocytosis of adeno-associated virus type 5 leads to accumulation of virus particles in the Golgi compartment

1 reference

12 December 2020

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

1 reference

12 December 2020

Comparative cardiac gene delivery of adeno-associated virus serotypes 1-9 reveals that AAV6 mediates the most efficient transduction in mouse heart

1 reference

12 December 2020

Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion

1 reference

12 December 2020

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

1 reference

12 December 2020

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

1 reference

12 December 2020

AAV6-βARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve

1 reference

12 December 2020

β2-Adrenergic Receptor Signaling in the Cardiac Myocyte is Modulated by Interactions With CXCR4

1 reference

12 December 2020

Widespread regional myocardial transfection by plasmid encoding Del-1 following retrograde coronary venous delivery

1 reference

12 December 2020

Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo

1 reference

12 December 2020

Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virus

1 reference

12 December 2020

SUMO1-dependent modulation of SERCA2a in heart failure

1 reference

12 December 2020

Efficient myocyte gene delivery with complete cardiac surgical isolation in situ

1 reference

12 December 2020

Tissue specific promoters improve specificity of AAV9 mediated transgene expression following intra-vascular gene delivery in neonatal mice.

1 reference

12 December 2020

Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart

1 reference

12 December 2020

Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

1 reference

12 December 2020

Mechanisms of gene silencing by double-stranded RNA

1 reference

12 December 2020

Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy

1 reference

12 December 2020

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue

1 reference

12 December 2020

Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade

1 reference

12 December 2020

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

1 reference

12 December 2020

Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a type 2 diabetic rat model

1 reference

12 December 2020

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

1 reference

12 December 2020

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

12 December 2020

Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury

1 reference

12 December 2020

Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase

1 reference

12 December 2020

Human heart failure: cAMP stimulation of SR Ca(2+)-ATPase activity and phosphorylation level of phospholamban

1 reference

12 December 2020

Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

1 reference

12 December 2020

Molecular evolution of adeno-associated virus for enhanced glial gene delivery

1 reference

12 December 2020

Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer.

1 reference

12 December 2020

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models

1 reference

12 December 2020

Uniform scale-independent gene transfer to striated muscle after transvenular extravasation of vector

1 reference

12 December 2020

Modulation of ventricular function through gene transfer in vivo

1 reference

12 December 2020

Rescuing the failing heart by targeted gene transfer

1 reference

12 December 2020

Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model

1 reference

12 December 2020

Effect of gene therapy on visual function in Leber's congenital amaurosis

1 reference

12 December 2020

Double oxygen-sensing vector system for robust hypoxia/ischemia-regulated gene induction in cardiac muscle in vitro and in vivo

1 reference

12 December 2020

Cardiac adenoviral S100A1 gene delivery rescues failing myocardium

1 reference

12 December 2020

A novel method for nonfluoroscopic catheter-based electroanatomical mapping of the heart. In vitro and in vivo accuracy results

1 reference

12 December 2020

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery

1 reference

12 December 2020

Pharmacokinetic analysis of coronary venous retroinfusion: A comparison with anterograde coronary artery drug administration using metoprolol as a tracer

1 reference

12 December 2020

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

1 reference

12 December 2020

Gene therapy targets in heart failure: the path to translation

1 reference

12 December 2020

Metabolic disturbances in non-alcoholic fatty liver disease.

1 reference

12 December 2020

Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer

1 reference

12 December 2020

Percutaneous transvenous cellular cardiomyoplasty. A novel nonsurgical approach for myocardial cell transplantation

1 reference

12 December 2020

Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.

1 reference

12 December 2020

Helper-dependent adenovirus vectors devoid of all viral genes cause less myocardial inflammation compared with first-generation adenovirus vectors

1 reference

12 December 2020

Gene delivery to human adult and embryonic cell-derived stem cells using biodegradable nanoparticulate polymeric vectors.

1 reference

12 December 2020

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

1 reference

12 December 2020

Adeno-associated viral vectors and their redirection to cell-type specific receptors

1 reference

12 December 2020

Intrapericardial administration of novel DNA formulations based on thermosensitive Poloxamer 407 gel.

1 reference

12 December 2020

AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect

1 reference

12 December 2020

Differential myocardial gene delivery by recombinant serotype-specific adeno-associated viral vectors

1 reference

12 December 2020

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins

1 reference

12 December 2020

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

1 reference

12 December 2020

Gutless adenovirus: last-generation adenovirus for gene therapy

1 reference

12 December 2020

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

1 reference

12 December 2020

Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression

1 reference

12 December 2020

Expression of sarcoplasmic reticulum Ca(2+)-ATPase and calsequestrin genes in rat heart during ontogenic development and aging.

1 reference

12 December 2020

Control of erythropoietin delivery by doxycycline in mice after intramuscular injection of adeno-associated vector

1 reference

12 December 2020

The next step in gene delivery: molecular engineering of adeno-associated virus serotypes

1 reference

12 December 2020

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

1 reference

12 December 2020

Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans

1 reference

12 December 2020

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

1 reference

12 December 2020

Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation

1 reference

12 December 2020

Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure

1 reference

12 December 2020

A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia

1 reference

12 December 2020

Progress and prospects: immune responses to viral vectors

1 reference

12 December 2020

Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters

1 reference

12 December 2020

Ultrarapid, highly efficient viral gene transfer to the heart

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

SDF-1α as a therapeutic stem cell homing factor in myocardial infarction

1 reference

12 December 2020

Gene delivery to the myocardium by intrapericardial injection.

1 reference

12 December 2020

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer

1 reference

12 December 2020

Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice

1 reference

12 December 2020

The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

1 reference

12 December 2020

Adeno-associated virus type 5 exploits two different entry pathways in human embryo fibroblasts

1 reference

12 December 2020

Intracellular transport of recombinant adeno-associated virus vectors

1 reference

12 December 2020

Development and validation of a robust and versatile one-plasmid regulated gene expression system.

1 reference

12 December 2020

Repeated and targeted transfer of angiogenic plasmids into the infarcted rat heart via ultrasound targeted microbubble destruction enhances cardiac repair.

1 reference

12 December 2020

Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart

1 reference

12 December 2020

Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury.

1 reference

12 December 2020

Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity

1 reference

12 December 2020

A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs.

1 reference

12 December 2020

Key protein alterations associated with hyperdynamic cardiac function: insights based on proteomic analysis of the protein phosphatase 1 inhibitor-1 overexpressing hearts.

1 reference

12 December 2020

Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

1 reference

12 December 2020

Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a

1 reference

12 December 2020

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

1 reference

12 December 2020

Catheter-based endomyocardial injection with real-time magnetic resonance imaging

1 reference

12 December 2020

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

1 reference

12 December 2020

The emerging role of Krüppel-like factors in endocrine-responsive cancers of female reproductive tissues

1 reference

12 December 2020

Adeno-associated virus 2 infection requires endocytosis through the CLIC/GEEC pathway.

1 reference

12 December 2020

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

1 reference

12 December 2020

S100A1: a calcium-modulating inotropic prototype for future clinical heart failure therapy

1 reference

12 December 2020

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery

1 reference

12 December 2020

Injection of adeno-associated viral vector encoding vascular endothelial growth factor gene in infarcted swine myocardium: MR measurements of left ventricular function and strain.

1 reference

12 December 2020

Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance

1 reference

12 December 2020

Regulation of gene expression in vivo following transduction by two separate rAAV vectors

1 reference

12 December 2020

Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy

1 reference

12 December 2020

Complement is an essential component of the immune response to adeno-associated virus vectors

1 reference

12 December 2020

A translatable, closed recirculation system for AAV6 vector-mediated myocardial gene delivery in the large animal

1 reference

12 December 2020

SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells

1 reference

12 December 2020

Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo

1 reference

12 December 2020

SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure

1 reference

12 December 2020

CXCR4 modulates contractility in adult cardiac myocytes

1 reference

12 December 2020

Neutralizing antibodies against adeno-associated viruses in inflammatory bowel disease patients: implications for gene therapy

1 reference

12 December 2020

Heart-targeted adeno-associated viral vectors selected by in vivo biopanning of a random viral display peptide library

1 reference

12 December 2020

Effect of viral dose on neutralizing antibody response and transgene expression after AAV1 vector re-administration in mice

1 reference

12 December 2020

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

1 reference

12 December 2020

Strategies of conditional gene expression in myocardium: an overview.

1 reference

12 December 2020

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

1 reference

12 December 2020

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure

1 reference

12 December 2020

Recent advances in lentiviral vector development and applications

1 reference

12 December 2020

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

1 reference

12 December 2020

Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo

1 reference

12 December 2020

Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy

1 reference

12 December 2020

Incomplete retention after direct myocardial injection

1 reference

12 December 2020

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

1 reference

12 December 2020

Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1

1 reference

12 December 2020

Myocarditis following adeno-associated viral gene expression of human soluble TNF receptor (TNFRII-Fc) in baboon hearts.

1 reference

12 December 2020

Ultrasound- and liposome microbubble-mediated targeted gene transfer to cardiomyocytes in vivo accompanied by polyethylenimine.

1 reference

12 December 2020

10.1161/CIRCRESAHA.111.252981

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383712%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22383712%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

22383712

1 reference