(Q83640823)

English

First report of the safety, tolerability, and pharmacokinetics of the Src kinase inhibitor saracatinib (AZD0530) in Japanese patients with advanced solid tumours

scientific article published on 14 March 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

First report of the safety, tolerability, and pharmacokinetics of the Src kinase inhibitor saracatinib (AZD0530) in Japanese patients with advanced solid tumours (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

pharmacokinetics

1 reference

based on heuristic

inferred from title

11

object named as

Narikazu Boku

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Yasuhito Fujisaka

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Yusuke Onozawa

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Takayasu Kurata

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Hirofumi Yasui

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Isao Goto

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Kentaro Yamazaki

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Nozomu Machida

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Junichiro Watanabe

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Hitoshi Shimada

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Xiaojin Shi

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

14 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

31

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

108-114

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22415795%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

https://scigraph.springernature.com/pub.10.1007/s10637-012-9809-7

0 references

Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Future of personalized medicine in oncology: a systems biology approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SRC inhibitors as potential therapeutic agents for human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A renaissance for SRC

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased levels of active c-Src distinguish invasive from in situ lobular lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated SRC protein tyrosine kinase is overexpressed in late-stage human ovarian cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I safety, pharmacokinetics, and inhibition of SRC activity study of saracatinib in patients with solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of Src in solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethnic differences in drug metabolism and toxicity from chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular functions regulated by Src family kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src-family tyrosine kinases as therapeutic targets in advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted cancer therapies in the twenty-first century: lessons from imatinib

1 reference

https://pubmed.ncbi.nlm.nih.gov/22415795

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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