(Q83870604)

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Pharmacokinetic-pharmacodynamic (PK-PD) modeling of cardiovascular effects of metoprolol in spontaneously hypertensive rats: a microdialysis study

scientific article published on 30 May 2006

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Pharmacokinetic-pharmacodynamic (PK-PD) modeling of cardiovascular effects of metoprolol in spontaneously hypertensive rats: a microdialysis study (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

Christian Höcht

1

object named as

Christian Höcht

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Javier A W Opezzo

3

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Javier A W Opezzo

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Europe PubMed Central

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28 January 2020

5

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Carlos A Taira

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Carla Di Verniero

2

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Europe PubMed Central

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28 January 2020

Guillermo F Bramuglia

4

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Europe PubMed Central

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28 January 2020

publication date

30 May 2006

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Europe PubMed Central

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28 January 2020

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

373

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

310-318

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16733693%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

https://scigraph.springernature.com/pub.10.1007/s00210-006-0078-x

0 references

Catecholamine-stimulated lipolysis in adipocytes of spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of propranolol plasma level to beta-blockade during oral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical relevance of optimal pharmacokinetics in the treatment of hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentration-effect relationship of l-propranolol and metoprolol in spontaneous hypertensive rats after exercise-induced tachycardia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of a cardioselective (metoprolol) and a nonselective (propranolol) beta-adrenergic blocker on the response to dynamic exercise in normal men

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential development of vascular and cardiac hypertrophy in genetic hypertension. Relation to sympathetic function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiologic and pharmacokinetic determinants of the antihypertensive response to propranolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of methyldopa in aorta-coarctated rats using a microdialysis technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte responsiveness to norepinephrine in spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microdialysis--theory and application

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic modeling of metoprolol stereoisomers in spontaneously hypertensive rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Applicability of microdialysis as a technique for pharmacokinetic-pharmacodynamic (PK-PD) modeling of antihypertensive beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sympathetic system in hypertension. State-of-the-art review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic estimations from microdialysis data

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic/pharmacodynamic integration in drug development and dosage-regimen optimization for veterinary medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma levels and effects of metoprolol on blood pressure, adrenergic beta receptor blockade, and plasma renin activity in essential hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma microdialysis. A technique for continuous plasma sampling in freely moving rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microdialysis--principles and applications for studies in animals and man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of metoprolol enantiomers following single and multiple administration of racemate in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of microdialysis in pharmacokinetic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the sympathetic nervous system in human hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implications of cytochrome P450 interactions when prescribing medication for hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the anti-hypertensive response to beta-adrenoceptor blocking drugs in intact and adrenal-demedullated spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypotensive and renin-suppressing activities of propranolol in hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipolysis and beta-adrenergic receptor binding on adipocytes of spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human pharmacokinetic and pharmacodynamic studies on the atenolo (ICI 66,082), a new cardioselective beta-adrenoceptor blocking drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metoprolol kinetics and dose response in hypertensive patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian rhythm of blood pressure and the relation to cardiovascular events

1 reference

https://pubmed.ncbi.nlm.nih.gov/16733693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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