(Q83910679)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

review article

1 reference

title

Human stem cells and drug screening: opportunities and challenges (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Allison D Ebert

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Clive N Svendsen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

publication date

26 March 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

367-372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd3000

29 January 2020

exact match

0 references

cites work

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Human embryonic stem cells reveal recurrent genomic instability at 20q11.21.

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Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines

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Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes

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Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations

31 March 2020

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Reprogramming of human somatic cells to pluripotency with defined factors

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Induced pluripotent stem cell lines derived from human somatic cells

31 March 2020

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Guidelines and techniques for the generation of induced pluripotent stem cells

31 March 2020

1 reference

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

31 March 2020

1 reference

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

31 March 2020

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piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

31 March 2020

1 reference

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31 March 2020

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Induced pluripotent stem cells generated without viral integration

31 March 2020

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Human induced pluripotent stem cells free of vector and transgene sequences

31 March 2020

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

31 March 2020

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

31 March 2020

1 reference

Upping the ante: recent advances in direct reprogramming

31 March 2020

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Generation of induced pluripotent stem cells using recombinant proteins

31 March 2020

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Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

31 March 2020

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

31 March 2020

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Japan fast-tracks stem-cell patent

31 March 2020

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Translating preclinical insights into effective human trials in ALS.

31 March 2020

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Design, power, and interpretation of studies in the standard murine model of ALS

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

31 March 2020

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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

31 March 2020

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ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

31 March 2020

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A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

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31 March 2020

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A clinical trial of creatine in ALS.

31 March 2020

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Preclinical assessment of cardiac toxicity

31 March 2020

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Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

31 March 2020

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Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells

31 March 2020

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31 March 2020

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Human stem cells as a model for cardiac differentiation and disease.

31 March 2020

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Identification of small molecules from human embryonic stem cells using metabolomics

31 March 2020

1 reference

High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells

31 March 2020

1 reference

Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells

31 March 2020

1 reference

A small molecule primes embryonic stem cells for differentiation

31 March 2020

1 reference

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

31 March 2020

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A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging.

31 March 2020

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Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos

31 March 2020

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Derivation of midbrain dopamine neurons from human embryonic stem cells

31 March 2020

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Genes associated with Parkinson syndrome

31 March 2020

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Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation

31 March 2020

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Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

31 March 2020

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Induced pluripotent stem cells from a spinal muscular atrophy patient

31 March 2020

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Disease-specific induced pluripotent stem cells

31 March 2020

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

31 March 2020

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The survival motor neuron protein in spinal muscular atrophy

31 March 2020

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Identification and characterization of a spinal muscular atrophy-determining gene

31 March 2020

1 reference

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

31 March 2020

1 reference

Correlation between severity and SMN protein level in spinal muscular atrophy

31 March 2020

1 reference

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

31 March 2020

1 reference

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRD3000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20339370%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference