(Q84006420)

English

Oral enzastaurin in prostate cancer: a two-cohort phase II trial in patients with PSA progression in the non-metastatic castrate state and following docetaxel-based chemotherapy for castrate metastatic disease

scientific article published on 06 April 2010

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20369375%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Oral enzastaurin in prostate cancer: a two-cohort phase II trial in patients with PSA progression in the non-metastatic castrate state and following docetaxel-based chemotherapy for castrate metastatic disease (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20369375%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

phase II clinical trial

1 reference

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author name string

Robert Dreicer

1

1 reference

Europe PubMed Central

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30 January 2020

Jorge Garcia

2

1 reference

Europe PubMed Central

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30 January 2020

Maha Hussain

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20369375%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Brian Rini

4

1 reference

Europe PubMed Central

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30 January 2020

Nicholas Vogelzang

5

1 reference

Europe PubMed Central

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30 January 2020

Sandy Srinivas

6

1 reference

Europe PubMed Central

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30 January 2020

Bradley Somer

7

1 reference

Europe PubMed Central

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30 January 2020

Yan D Zhao

8

1 reference

Europe PubMed Central

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30 January 2020

Marek Kania

9

1 reference

Europe PubMed Central

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30 January 2020

Derek Raghavan

10

1 reference

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30 January 2020

publication date

6 April 2010

1 reference

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30 January 2020

Investigational New Drugs

1 reference

Europe PubMed Central

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30 January 2020

29

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30 January 2020

1441-1448

1 reference

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30 January 2020

6

1 reference

Europe PubMed Central

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30 January 2020

https://scigraph.springernature.com/pub.10.1007/s10637-010-9428-0

0 references

Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical outcome after radical prostatectomy or external beam radiation therapy for patients with clinically localized prostate carcinoma in the prostate specific antigen era

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The case for secondary hormonal therapies in the chemotherapy age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer statistics, 2009

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of radical prostatectomy for localized prostate cancer in the era of prostate-specific antigen: an overview of the Department of Defense Center for Prostate Disease Research national database

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimal two-stage designs for phase II clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The therapeutic role of targeting protein kinase C in solid and hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current status of cytotoxic chemotherapy in patients with metastatic prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staurosporine analogues - pharmacological toys or useful antitumour agents?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying the development of androgen-independent prostate cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploitation of protein kinase C: a useful target for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I dose escalation and pharmacokinetic study of enzastaurin, an oral protein kinase C beta inhibitor, in patients with advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C targeting in antineoplastic treatment strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

National practice patterns and time trends in androgen ablation for localized prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKC at a glance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural history of rising serum prostate-specific antigen in men with castrate nonmetastatic prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of protein kinase C isoenzymes in benign hyperplasia and carcinoma of prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20369375

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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