(Q84278833)

English

A pharmacodynamic Markov mixed-effects model for determining the effect of exposure to certolizumab pegol on the ACR20 score in patients with rheumatoid arthritis

scientific article published on 22 July 2009

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scholarly article

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3 February 2020

A pharmacodynamic Markov mixed-effects model for determining the effect of exposure to certolizumab pegol on the ACR20 score in patients with rheumatoid arthritis (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19626001%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

rheumatoid arthritis

1 reference

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inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

Mats O Karlsson

5

object named as

M O Karlsson

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3 February 2020

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B D Lacroix

1

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3 February 2020

M R Lovern

2

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3 February 2020

A Stockis

3

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3 February 2020

M L Sargentini-Maier

4

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3 February 2020

L E Friberg

6

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3 February 2020

publication date

22 July 2009

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3 February 2020

Clinical Pharmacology & Therapeutics

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3 February 2020

86

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3 February 2020

4

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3 February 2020

387-395

1 reference

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3 February 2020

Cytokine pathways and joint inflammation in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of cytokines in inflammatory synovitis. The coordinate regulation of intercellular adhesion molecule 1 and HLA class I and class II antigens in rheumatoid synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor inhibitors for rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-cont

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of action of certolizumab pegol (CDP870): in vitro comparison with other anti-tumor necrosis factor alpha agents

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: a phase II double-blinded, randomized, dose-escalating trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group st

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy and safety of certolizumab pegol plus methotrexate in active rheumatoid arthritis: the RAPID 2 study. A randomised controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials. The Committee on Outcome Measures in Rheumatoid Arthritis Clinical Trials

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Population pharmacokinetic and pharmacodynamic modeling of etanercept using logistic regression analysis

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

A pharmacodynamic Markov mixed-effects model for the effect of temazepam on sleep.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of different methods used to assess disease activity in rheumatoid arthritis: analyses of abatacept clinical trial data

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Exposure-response modeling using latent variables for the efficacy of a JAK3 inhibitor administered to rheumatoid arthritis patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2009.136

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2009.136

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19626001%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19626001%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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