(Q84346351)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Clearance of mutant huntingtin (English)

1 reference

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4 February 2020

author name string

Xiao-Jiang Li

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

He Li

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Shihua Li

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

publication date

1 July 2010

1 reference

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4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

volume

6

1 reference

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4 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

page(s)

663-664

1 reference

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

4 February 2020

cites work

1 reference

12 December 2020

Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation

1 reference

12 December 2020

Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: exclusion of proteasome activator REGgamma as a therapeutic target

1 reference

12 December 2020

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

12 December 2020

Proteolysis: from the lysosome to ubiquitin and the proteasome

1 reference

12 December 2020

Consequences of the selective blockage of chaperone-mediated autophagy

1 reference

12 December 2020

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

12 December 2020

Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice

1 reference

12 December 2020

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 reference

12 December 2020

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

12 December 2020

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

1 reference

12 December 2020

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

1 reference

12 December 2020

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

12 December 2020

Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis

1 reference

12 December 2020

Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth.

1 reference

12 December 2020

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

12 December 2020

Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseases

1 reference

12 December 2020

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

1 reference

12 December 2020

The roles of intracellular protein-degradation pathways in neurodegeneration

1 reference

12 December 2020

Impairment of the ubiquitin-proteasome system by protein aggregation

1 reference

12 December 2020

Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons

1 reference

12 December 2020

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease

1 reference

12 December 2020

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

12 December 2020

Induction of autophagy in axonal dystrophy and degeneration

1 reference

12 December 2020

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

1 reference

12 December 2020

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

1 reference

12 December 2020

Autophagy is activated for cell survival after endoplasmic reticulum stress

1 reference

12 December 2020

Huntington's disease: degradation of mutant huntingtin by autophagy

1 reference

12 December 2020

Rodent genetic models of Huntington disease

1 reference

12 December 2020

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

1 reference

12 December 2020

A role for ubiquitin in selective autophagy

1 reference

12 December 2020

How to interpret LC3 immunoblotting

1 reference

12 December 2020

Neurite outgrowth in PC12 cells. Distinguishing the roles of ubiquitylation and ubiquitin-dependent proteolysis

1 reference

12 December 2020

A block of autophagy in lysosomal storage disorders

1 reference

12 December 2020

Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration

1 reference

12 December 2020

Proteasome degrades soluble expanded polyglutamine completely and efficiently

1 reference

12 December 2020

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

12 December 2020

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

12 December 2020

p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum

1 reference

12 December 2020

Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity.

1 reference

12 December 2020

Small molecule regulators of autophagy identified by an image-based high-throughput screen

1 reference

12 December 2020

Autophagy in the Pathogenesis of Disease

1 reference

12 December 2020

Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease

1 reference

12 December 2020

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

1 reference

12 December 2020

Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins

1 reference

12 December 2020

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

12 December 2020

N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease

1 reference

12 December 2020

Autophagic stress in neuronal injury and disease.

1 reference

12 December 2020

Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain

1 reference

12 December 2020

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

1 reference

12 December 2020

Identifiers

DOI

10.4161/AUTO.6.5.12336

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20519964%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

20519964

1 reference