(Q84356942)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22688963%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants (English)

1 reference

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4 February 2020

2

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4 February 2020

author name string

Koichi Nakagawa

1

1 reference

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4 February 2020

Toshiyuki Takehara

3

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4 February 2020

Yuta Onodera

4

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4 February 2020

Chiaki Hamanishi

5

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4 February 2020

Masao Akagi

6

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4 February 2020

Kanji Fukuda

7

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4 February 2020

publication date

12 June 2012

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4 February 2020

published in

Inflammation Research

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4 February 2020

volume

61

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4 February 2020

issue

10

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4 February 2020

page(s)

1093-1100

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Mechano-transduction in periodontal ligament cells identifies activated states of MAP-kinases p42/44 and p38-stress kinase as a mechanism for MMP-13 expression

4 February 2020

cites work

1 reference

12 December 2020

Smooth muscle actin determines mechanical force-induced p38 activation

1 reference

12 December 2020

Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage

1 reference

12 December 2020

Rho/ROCK and MEK/ERK activation by transforming growth factor-alpha induces articular cartilage degradation

1 reference

12 December 2020

The small GTPase Rho mediates articular chondrocyte phenotype and morphology in response to interleukin-1alpha and insulin-like growth factor-I.

1 reference

12 December 2020

Joint injury in young adults and risk for subsequent knee and hip osteoarthritis

1 reference

12 December 2020

Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage.

1 reference

12 December 2020

Rho kinase-dependent CCL20 induced by dynamic compression of human chondrocytes.

1 reference

12 December 2020

Rho GTPases in cell biology

1 reference

12 December 2020

Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain

1 reference

12 December 2020

Rho GTPases and signaling networks

1 reference

12 December 2020

Cyclic compression loaded on cartilage explants enhances the production of reactive oxygen species

1 reference

12 December 2020

The effects of matrix compression on proteoglycan metabolism in articular cartilage explants

1 reference

12 December 2020

Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes.

1 reference

12 December 2020

RhoA/ROCK signaling regulates Sox9 expression and actin organization during chondrogenesis.

1 reference

12 December 2020

Mechanical injury potentiates proteoglycan catabolism induced by interleukin-6 with soluble interleukin-6 receptor and tumor necrosis factor alpha in immature bovine and adult human articular cartilage

1 reference

12 December 2020

Collagenase-3 (matrix metalloprotease 13) is preferentially localized in the deep layer of human arthritic cartilage in situ: in vitro mimicking effect by transforming growth factor beta

1 reference

12 December 2020

Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects

1 reference

12 December 2020

Hyaluronan inhibits matrix metalloproteinase-13 in human arthritic chondrocytes via CD44 and P38.

1 reference

12 December 2020

Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure

1 reference

12 December 2020

Influence of p38MAPK inhibition on IL-1beta-stimulated human chondrocytes: a microarray approach.

1 reference

12 December 2020

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis

1 reference

12 December 2020

Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells.

1 reference

12 December 2020

Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase

1 reference

12 December 2020

RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner.

1 reference

12 December 2020

Hyaluronan reversed proteoglycan synthesis inhibited by mechanical stress: possible involvement of antioxidant effect.

1 reference

12 December 2020

RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells

1 reference

12 December 2020

Improved bioengineered cartilage tissue formation following cyclic compression is dependent on upregulation of MT1-MMP

1 reference

12 December 2020

Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans

1 reference

12 December 2020

Osteoarthritis of the knee and associated factors of age and obesity: effects on gait

1 reference

12 December 2020

Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament

1 reference

12 December 2020

The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants

1 reference

12 December 2020

Alleviating effects of AS1892802, a Rho kinase inhibitor, on osteoarthritic disorders in rodents

1 reference

12 December 2020

Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis.

1 reference

12 December 2020

Regulation of subchondral bone osteoblast metabolism by cyclic compression

1 reference

12 December 2020

Osteoarthritis year 2010 in review: pathomechanisms

1 reference

12 December 2020

A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage.

1 reference

12 December 2020

MAPKs are essential upstream signaling pathways in proteolytic cartilage degradation--divergence in pathways leading to aggrecanase and MMP-mediated articular cartilage degradation.

1 reference

12 December 2020

Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation

1 reference

12 December 2020

Mechanical injury of cartilage explants causes specific time-dependent changes in chondrocyte gene expression

1 reference

12 December 2020

Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3

1 reference

12 December 2020

Regulation of SOX9 mRNA in human articular chondrocytes involving p38 MAPK activation and mRNA stabilization

1 reference

12 December 2020

Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes

1 reference

12 December 2020