(Q84395876)

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DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung

scientific article published on 14 June 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543864%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543864%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

neuroendocrine carcinoma

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tumor initiation

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T Shibata

1

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5 February 2020

A Kokubu

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20543864%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

M Miyamoto

3

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Europe PubMed Central

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5 February 2020

F Hosoda

4

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5 February 2020

M Gotoh

5

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5 February 2020

K Tsuta

6

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5 February 2020

H Asamura

7

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5 February 2020

Y Matsuno

8

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Europe PubMed Central

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5 February 2020

T Kondo

9

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5 February 2020

I Imoto

10

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5 February 2020

J Inazawa

11

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5 February 2020

S Hirohashi

12

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5 February 2020

publication date

14 June 2010

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5 February 2020

1 reference

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5 February 2020

29

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5 February 2020

33

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5 February 2020

4671-4681

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5 February 2020

https://scigraph.springernature.com/pub.10.1038/onc.2010.217

0 references

Neuroendocrine neoplasms of the lung: a prognostic spectrum.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

A perivascular niche for brain tumor stem cells

1 reference

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Transcriptional activation by AP-2alpha is modulated by the oncogene DEK

1 reference

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31 March 2020

DEK Expression is controlled by E2F and deregulated in diverse tumor types

1 reference

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31 March 2020

The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription

1 reference

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31 March 2020

p300/CBP-associated factor drives DEK into interchromatin granule clusters.

1 reference

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31 March 2020

Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia

1 reference

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31 March 2020

Malignancy-associated X chromosome allelic losses in foregut endocrine neoplasms: further evidence from lung tumors

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31 March 2020

DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer

1 reference

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31 March 2020

Molecular cloning of t(2;7)(p24.3;p14.2), a novel chromosomal translocation in myelodysplastic syndrome-derived acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

"Stemness" genomics law governs clinical behavior of human cancer: implications for decision making in disease management

1 reference

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Identification of selective inhibitors of cancer stem cells by high-throughput screening

1 reference

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31 March 2020

Bronchopulmonary neuroendocrine tumors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Clinicopathological significance of DEK overexpression in serous ovarian tumors

1 reference

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31 March 2020

Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Two prognostically significant subtypes of high-grade lung neuroendocrine tumours independent of small-cell and large-cell neuroendocrine carcinomas identified by gene expression profiles.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.

1 reference

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Melanoma proliferation and chemoresistance controlled by the DEK oncogene

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Regulation of histone acetyltransferase activity of p300 and PCAF by proto-oncogene protein DEK.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Generation of germline-competent induced pluripotent stem cells

1 reference

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MLLT3 regulates early human erythroid and megakaryocytic cell fate

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

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Cancer stem cells and the ontogeny of lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Neuro-endocrine tumours of the lung. A review of relevant pathological and molecular data.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

31 March 2020

Molecular and cellular biology of small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

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Genome regulation by polycomb and trithorax proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.217

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The lysine-specific demethylase 1 is required for cell proliferation in both p53-dependent and -independent manners

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EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma

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Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer

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Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.

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Intron Removal Requires Proofreading of U2AF/3' Splice Site Recognition by DEK

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Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma

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Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

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The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

1 reference

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Typical and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization

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Epigenetic stem cell signature in cancer

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Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions.

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The human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7

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Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo

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DEK proto-oncogene expression interferes with the normal epithelial differentiation program.

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Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation

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7 January 2021

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