(Q84639319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808264%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Human B cells differentiate into granzyme B-secreting cytotoxic B lymphocytes upon incomplete T-cell help (English)

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9 February 2020

8

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9 February 2020

Gerd Ulrich Nienhaus

12

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9 February 2020

author name string

Magdalena Hagn

1

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9 February 2020

Kai Sontheimer

2

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9 February 2020

Karen Dahlke

3

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9 February 2020

Sabine Brueggemann

4

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9 February 2020

Christof Kaltenmeier

5

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9 February 2020

Thamara Beyer

6

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9 February 2020

Stefanie Hofmann

7

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9 February 2020

Thomas F E Barth

9

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9 February 2020

Dorit Fabricius

10

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9 February 2020

Kyrylo Tron

11

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9 February 2020

Thomas Simmet

13

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9 February 2020

Hubert Schrezenmeier

14

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9 February 2020

Bernd Jahrsdörfer

15

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9 February 2020

publication date

2 August 2011

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Immunology & Cell Biology

9 February 2020

published in

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9 February 2020

volume

90

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9 February 2020

issue

4

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9 February 2020

page(s)

457-467

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Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

9 February 2020

cites work

1 reference

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7 January 2021

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

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7 January 2021

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

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Interleukin-21 mRNA expression during virus infections

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7 January 2021

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

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7 January 2021

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

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7 January 2021

IL-21: a novel IL-2-family lymphokine that modulates B, T, and natural killer cell responses

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7 January 2021

Biology of IL-21 and the IL-21 receptor

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7 January 2021

B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation.

1 reference

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7 January 2021

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

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7 January 2021

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

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7 January 2021

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

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7 January 2021

The secretory synapse: the secrets of a serial killer

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7 January 2021

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

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7 January 2021

NK cells and cancer immunosurveillance.

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7 January 2021

Regulation of tumor immunity: the role of NKT cells

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7 January 2021

NK cells and NKT cells in innate defense against viral infections

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7 January 2021

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7 January 2021

B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms

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7 January 2021

Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.

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7 January 2021

Interleukin-21: biology and application to cancer therapy

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7 January 2021

IL-21 is required to control chronic viral infection

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7 January 2021

Heat shock protein 70 (Hsp70): membrane location, export and immunological relevance

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7 January 2021

Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity

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7 January 2021

From cancer immunosurveillance to cancer immunotherapy

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7 January 2021

Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

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7 January 2021

Targeting HSP90 for cancer therapy

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7 January 2021

Calcium-dependent activation of interleukin-21 gene expression in T cells

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7 January 2021

Interleukin 21: a cytokine/cytokine receptor system that has come of age

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7 January 2021

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

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7 January 2021

Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors

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7 January 2021

On the role of self-recognition in T cell responses to foreign antigen

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7 January 2021

HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control.

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7 January 2021

HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function

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7 January 2021

A central role of perforin in cytolysis?

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7 January 2021

Delivering the kiss of death: progress on understanding how perforin works

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7 January 2021

Granzyme B: a natural born killer

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7 January 2021

CTL secretory lysosomes: biogenesis and secretion of a harmful organelle

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7 January 2021

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

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7 January 2021

Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

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7 January 2021

Mechanism of adenovirus-mediated endosome lysis: role of the intact adenovirus capsid structure

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7 January 2021

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

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7 January 2021

Cell surface-bound heat shock protein 70 (Hsp70) mediates perforin-independent apoptosis by specific binding and uptake of granzyme B.

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7 January 2021

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

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7 January 2021

Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion.

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7 January 2021

Good prognosis cytogenetics in B-cell chronic lymphocytic leukemia is associated in vitro with low susceptibility to apoptosis and enhanced immunogenicity

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7 January 2021

Immunostimulatory oligodeoxynucleotides induce apoptosis of B cell chronic lymphocytic leukemia cells.

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7 January 2021

B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides

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7 January 2021

Identifiers

DOI

10.1038/ICB.2011.64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21808264%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference