(Q84732981)

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Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of

scientific article published on 03 August 2012

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Europe PubMed Central

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10 February 2020

Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of infarct size in 1,074 mice (English)

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10 February 2020

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Roberto Bolli

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10 February 2020

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Yiru Guo

1

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10 February 2020

Michael P Flaherty

2

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10 February 2020

Wen-Jian Wu

3

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10 February 2020

Wei Tan

4

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10 February 2020

Xiaoping Zhu

5

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10 February 2020

Qianhong Li

6

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10 February 2020

publication date

3 August 2012

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10 February 2020

Basic Research in Cardiology

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10 February 2020

107

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10 February 2020

5

1 reference

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10 February 2020

288

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10 February 2020

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pH paradox in ischemia-reperfusion injury to cardiac myocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial protection by brief ischemia in noncardiac tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epicardial Temperature is a Major Predictor of Myocardial Infarct Size in Dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial temperature in acute myocardial infarction: protection with mild regional hypothermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased myocardial tumor necrosis factor-alpha in a crystalloid-perfused model of cardiac ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothermia preserves function and signaling for mitochondrial biogenesis during subsequent ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothermia extends the cardioprotection by ischaemic preconditioning to coronary artery occlusions of longer duration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of an early and a late phase of ischemic preconditioning in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and cellular mechanisms of myocardial stunning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic preconditioning and myocardial hypothermia in rabbits with prolonged coronary artery occlusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic preconditioning increases iNOS transcript levels in conscious rabbits via a nitric oxide-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of post-infarct ventricular rupture: time course, strain- and gender-dependency, tensile strength, and histopathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pore way to die

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRL mice fail to heal the heart in response to ischemia-reperfusion injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Late preconditioning induced by NO donors, adenosine A1 receptor agonists, and delta1-opioid receptor agonists is mediated by iNOS

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testosterone enhances early cardiac remodeling after myocardial infarction, causing rupture and degrading cardiac function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No loss of cardioprotection by postconditioning in connexin 43-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcification of myocardial necrosis is common in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preconditioning: a paradigm shift in the biology of myocardial ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial reperfusion injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ensemble adaptive network-based fuzzy inference system with weighted arithmetical mean and application to diagnosis of optic nerve disease from visual-evoked potential signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acrolein consumption exacerbates myocardial ischemic injury and blocks nitric oxide-induced PKCepsilon signaling and cardioprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of TNF-alpha receptors p55 and p75 in acute myocardial ischemia/reperfusion injury and late preconditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of cardioprotection with ageing.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beneficial effects of postinfarct cytokine combination therapy are sustained during long-term follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translating novel strategies for cardioprotection: the Hatter Workshop Recommendations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic cytokines for cardiac repair: mobilization of bone marrow cells and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of an NIH consortium for preclinicAl AssESsment of CARdioprotective therapies (CAESAR): a paradigm shift in studies of infarct size limitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic preconditioning limits infarct size following regional ischemia-reperfusion in in situ mouse hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aldose reductase-deficient mice develop nephrogenic diabetes insipidus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an essential role of cyclooxygenase-2 as a mediator of the late phase of ischemic preconditioning in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted deletion of the A3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An essential role of the JAK-STAT pathway in ischemic preconditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene Therapy With Inducible Nitric Oxide Synthase Protects Against Myocardial Infarction via a Cyclooxygenase-2–Dependent Mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varying susceptibility to myocardial infarction among C57BL/6 mice of different genetic background.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-alpha-induced cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha does not modulate ischemia/reperfusion injury in naïve myocardium but is essential for the development of late preconditioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial protection at a crossroads: the need for translation into clinical therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"Normothermic range" temperature affects myocardial infarct size

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging increases ischemia-reperfusion injury in the isolated, buffer-perfused heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial ischemia and reperfusion: a murine model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of temperature on myocardial infarction in swine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22864681

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00395-012-0288-Y

1 reference

Europe PubMed Central

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10 February 2020

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Europe PubMed Central

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10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22864681%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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