(Q84767205)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

review article

1 reference

title

Molecular pathogenesis of diffuse large B-cell lymphoma (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

diffuse large B-cell lymphoma

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Christof Schneider

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Laura Pasqualucci

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Riccardo Dalla-Favera

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

publication date

1 May 2011

1 reference

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Seminars in Diagnostic Pathology

10 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

28

1 reference

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10 February 2020

page(s)

167-177

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10 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma

10 February 2020

cites work

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12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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12 December 2020

Heterologous promoters fused to BCL6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation

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12 December 2020

p16(INK4a) gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas

1 reference

12 December 2020

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

12 December 2020

Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor

1 reference

12 December 2020

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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12 December 2020

Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma

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12 December 2020

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

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12 December 2020

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

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12 December 2020

Cellular origin of human B-cell lymphomas.

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12 December 2020

Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells

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12 December 2020

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

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12 December 2020

INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene

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12 December 2020

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas

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12 December 2020

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

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12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

12 December 2020

Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

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12 December 2020

Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line

1 reference

12 December 2020

Primary mediastinal B-cell lymphoma: a review of pathology and management

1 reference

12 December 2020

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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12 December 2020

Mechanisms of chromosomal translocations in B cell lymphomas

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12 December 2020

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

12 December 2020

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

1 reference

12 December 2020

Mediastinal (thymic) large B-cell lymphoma: where do we stand?

1 reference

12 December 2020

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

1 reference

12 December 2020

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

12 December 2020

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

1 reference

12 December 2020

Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas

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12 December 2020

Acetylation inactivates the transcriptional repressor BCL6.

1 reference

12 December 2020

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

12 December 2020

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

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12 December 2020

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

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12 December 2020

BCL6 controls the expression of the B7-1/CD80 costimulatory receptor in germinal center B cells

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12 December 2020

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

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12 December 2020

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

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12 December 2020

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

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12 December 2020

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

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12 December 2020

Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray

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12 December 2020

Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation

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12 December 2020

Immunohistochemical expression patterns of germinal center and activation B-cell markers correlate with prognosis in diffuse large B-cell lymphoma.

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12 December 2020

Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma.

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12 December 2020

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

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12 December 2020

AID is required for c-myc/IgH chromosome translocations in vivo

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12 December 2020

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

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12 December 2020

Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas

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12 December 2020

The human thymus contains a novel population of B lymphocytes

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12 December 2020

Thymic medullary cells expressing B lymphocyte antigens

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12 December 2020

t(3;22)(q27;q11): a novel translocation associated with diffuse non-Hodgkin's lymphoma

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12 December 2020

MYC rearrangement and translocations involving band 8q24 in diffuse large cell lymphomas

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12 December 2020

Intraclonal generation of antibody mutants in germinal centres

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12 December 2020

Maturation of the immune response in germinal centers

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12 December 2020

Cloning of bcl-6, the locus involved in chromosome translocations affecting band 3q27 in B-cell lymphoma.

1 reference

12 December 2020

Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas

1 reference

12 December 2020

p53 mutations are associated with histologic transformation of follicular lymphoma

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12 December 2020

LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

1 reference

12 December 2020

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

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12 December 2020

Molecular cloning of the breakpoint for 3q27 translocation in B-cell lymphomas and leukemias.

1 reference

12 December 2020

Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma

1 reference

12 December 2020

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1 reference

12 December 2020

Frequent somatic hypermutation of the 5' noncoding region of the BCL6 gene in B-cell lymphoma

1 reference

12 December 2020

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

1 reference

12 December 2020

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene

1 reference

12 December 2020

BCL-6 expression during B-cell activation.

1 reference

12 December 2020

Clonal selection and learning in the antibody system

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12 December 2020

Sequential triggering of apoptosis, somatic mutation and isotype switch during germinal center development.

1 reference

12 December 2020

Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation

1 reference

12 December 2020

A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma. The Non-Hodgkin's Lymphoma Classification Project

1 reference

12 December 2020

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

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12 December 2020

Prognostic significance of Bcl-2 protein expression and Bcl-2 gene rearrangement in diffuse aggressive non-Hodgkin's lymphoma

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12 December 2020

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

1 reference

12 December 2020

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

1 reference

12 December 2020

PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage

1 reference

12 December 2020

Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

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12 December 2020

Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

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12 December 2020

A microRNA polycistron as a potential human oncogene

1 reference

12 December 2020

NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

1 reference

12 December 2020

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells

1 reference

12 December 2020

Favorable outcome of primary mediastinal large B-cell lymphoma in a single institution: the British Columbia experience

1 reference

12 December 2020

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

1 reference

12 December 2020

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

1 reference

12 December 2020

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination.

1 reference

12 December 2020

The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes

1 reference

12 December 2020

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

1 reference

12 December 2020

Aberrant NF-kappaB signaling in lymphoma: mechanisms, consequences, and therapeutic implications

1 reference

12 December 2020

Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR.

1 reference

12 December 2020

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

1 reference

12 December 2020

Frequent occurrence of deletions in primary mediastinal B-cell lymphoma

1 reference

12 December 2020

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

1 reference

12 December 2020

PIK3CA mutations are mutually exclusive with PTEN loss in diffuse large B-cell lymphoma

1 reference

12 December 2020

Further delineation of chromosomal consensus regions in primary mediastinal B-cell lymphomas: an analysis of 37 tumor samples using high-resolution genomic profiling (array-CGH).

1 reference

12 December 2020

Mutations in the DNA-binding codons of TP53, which are associated with decreased expression of TRAILreceptor-2, predict for poor survival in diffuse large B-cell lymphoma

1 reference

12 December 2020

Germinal centres: role in B-cell physiology and malignancy

1 reference

12 December 2020

AID is required for germinal center-derived lymphomagenesis

1 reference

12 December 2020

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

1 reference

12 December 2020

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

1 reference

12 December 2020

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

1 reference

12 December 2020

Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.

1 reference

12 December 2020

Stromal gene signatures in large-B-cell lymphomas

1 reference

12 December 2020

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

1 reference

12 December 2020

The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.

1 reference

12 December 2020

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.

1 reference

12 December 2020

Frequent inactivation of A20 in B-cell lymphomas

1 reference

12 December 2020

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

1 reference

12 December 2020

Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma

1 reference

12 December 2020

Molecular outcome prediction in diffuse large-B-cell lymphoma.

1 reference

12 December 2020

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

1 reference

12 December 2020

A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy

1 reference

12 December 2020

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

1 reference

12 December 2020

Regulation of adaptive immunity by the innate immune system

1 reference

12 December 2020

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

1 reference

12 December 2020

Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

1 reference

12 December 2020

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

12 December 2020

Pathogenesis of diffuse large B cell lymphoma

1 reference

12 December 2020

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

1 reference

12 December 2020

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

1 reference

12 December 2020

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

1 reference

12 December 2020

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

1 reference

12 December 2020

Oncogenically active MYD88 mutations in human lymphoma

1 reference

12 December 2020

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

1 reference

12 December 2020

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

1 reference

12 December 2020

The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications

1 reference

12 December 2020

10.1053/J.SEMDP.2011.04.001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21842702%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference