(Q84768063)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19850048%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure (English)

1 reference

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10 February 2020

author name string

Isamu Mizote

1

1 reference

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10 February 2020

Osamu Yamaguchi

2

1 reference

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10 February 2020

Shungo Hikoso

3

1 reference

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10 February 2020

Toshihiro Takeda

4

1 reference

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10 February 2020

Manabu Taneike

5

1 reference

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10 February 2020

Takafumi Oka

6

1 reference

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10 February 2020

Takahito Tamai

7

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10 February 2020

Jota Oyabu

8

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10 February 2020

Yasushi Matsumura

9

1 reference

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10 February 2020

Kazuhiko Nishida

10

1 reference

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10 February 2020

Issei Komuro

11

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10 February 2020

Masatsugu Hori

12

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10 February 2020

Kinya Otsu

13

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10 February 2020

publication date

20 October 2009

1 reference

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Journal of Molecular and Cellular Cardiology

10 February 2020

published in

1 reference

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10 February 2020

volume

48

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10 February 2020

issue

2

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10 February 2020

page(s)

302-309

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Controversies in ventricular remodelling

10 February 2020

cites work

1 reference

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Redefining the roles of p38 and JNK signaling in cardiac hypertrophy: dichotomy between cultured myocytes and animal models

7 January 2021

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Stress-activated MAP kinases in cardiac remodeling and heart failure; new insights from transgenic studies

7 January 2021

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The role of apoptosis signal-regulating kinase 1 in cardiomyocyte apoptosis

7 January 2021

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

7 January 2021

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Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

7 January 2021

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Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

7 January 2021

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TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.

7 January 2021

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Transgenic mice with cardiac-specific over-expression of MLK7 have increased mortality when exposed to chronic beta-adrenergic stimulation

7 January 2021

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

7 January 2021

1 reference

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A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

7 January 2021

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Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

7 January 2021

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Axin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activation

7 January 2021

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MEKK4 is an effector of the embryonic TRAF4 for JNK activation

7 January 2021

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Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes

7 January 2021

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GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

7 January 2021

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Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

7 January 2021

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Ablation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.

7 January 2021

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Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy

7 January 2021

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Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

7 January 2021

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The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

7 January 2021

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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

7 January 2021

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A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

7 January 2021

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Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?

7 January 2021

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Apoptosis in the failing human heart

7 January 2021

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A mechanistic role for cardiac myocyte apoptosis in heart failure

7 January 2021

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MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3beta

7 January 2021

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The specificities of protein kinase inhibitors: an update

7 January 2021

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Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity

7 January 2021

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STRESS signaling pathways that modulate cardiac myocyte apoptosis

7 January 2021

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Mitogen-activated protein kinase cascades as regulators of stress responses

7 January 2021

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Involvement of reactive oxygen species-mediated NF-kappa B activation in TNF-alpha-induced cardiomyocyte hypertrophy

7 January 2021

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The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model

7 January 2021

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gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress

7 January 2021

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The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B

7 January 2021

1 reference

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Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy

7 January 2021

1 reference

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10.1016/J.YJMCC.2009.10.010

7 January 2021

Identifiers

DOI

1 reference

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10 February 2020

1 reference