(Q84908928)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22937789%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

S-MDM4 mRNA overexpression indicates a poor prognosis and marks a potential therapeutic target in chronic lymphocytic leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22937789%20AND%20SRC:MED&resulttype=core&format=json

chronic lymphocytic leukemia

12 February 2020

main subject

1 reference

Ling Liu

1

1 reference

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12 February 2020

Lei Fan

2

1 reference

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12 February 2020

Cheng Fang

3

1 reference

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12 February 2020

Zhi-Jian Zou

4

1 reference

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12 February 2020

Shu Yang

5

1 reference

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12 February 2020

Li-Na Zhang

6

1 reference

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12 February 2020

Jian-Yong Li

7

1 reference

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12 February 2020

Wei Xu

8

1 reference

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12 February 2020

publication date

10 October 2012

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12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22937789%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

103

1 reference

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12 February 2020

issue

12

1 reference

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12 February 2020

page(s)

2056-2063

1 reference

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A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

12 February 2020

cites work

1 reference

12 December 2020

Mutational spectrum of p53 mutations in primary breast and ovarian tumors.

1 reference

12 December 2020

The regulation of the p53-mediated stress response by MDM2 and MDM4.

1 reference

12 December 2020

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

1 reference

12 December 2020

Targeting the MDM2-p53 interaction for cancer therapy

1 reference

12 December 2020

Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53

1 reference

12 December 2020

MDM4 (MDMX) and its Transcript Variants.

1 reference

12 December 2020

p53 expression in B-cell chronic lymphocytic leukemia: a marker of disease progression and poor prognosis.

1 reference

12 December 2020

Live or let die: the cell's response to p53

1 reference

12 December 2020

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

1 reference

12 December 2020

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

12 December 2020

Prognostic significance of ATM and TP53 deletions in Chinese patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Genomic aberrations and survival in chronic lymphocytic leukemia

1 reference

12 December 2020

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

1 reference

12 December 2020

MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild-type CLL with a poor cytotoxic response to Nutlin-3.

1 reference

12 December 2020

Mechanism of p53 stabilization by ATM after DNA damage

1 reference

12 December 2020

A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis

1 reference

12 December 2020

The prognostic significance of TP53 mutations in Chinese patients with chronic lymphocytic leukemia is independent of del(17p13).

1 reference

12 December 2020

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

1 reference

12 December 2020

Mdmx as an essential regulator of p53 activity

1 reference

12 December 2020

The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin

1 reference

12 December 2020

Identification of a domain within MDMX-S that is responsible for its high affinity interaction with p53 and high-level expression in mammalian cells

1 reference

12 December 2020

Using the biology of chronic lymphocytic leukemia to choose treatment

1 reference

12 December 2020

Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.

1 reference

12 December 2020

Control of apoptosis by p53.

1 reference

12 December 2020

Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial.

1 reference

12 December 2020

p53 and human cancer: the first ten thousand mutations.

1 reference

12 December 2020

P53, MDM-2, BAX and BCL-2 and drug resistance in chronic lymphocytic leukemia

1 reference

12 December 2020

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

1 reference

12 December 2020

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

1 reference

12 December 2020

When and how to treat chronic lymphocytic leukemia

1 reference

12 December 2020

Hdmx stabilizes Mdm2 and p53

1 reference

12 December 2020

CD38 as a prognostic factor in Chinese patients with chronic lymphocytic leukaemia

1 reference

12 December 2020

Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis.

1 reference

12 December 2020

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

1 reference

12 December 2020

HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis

1 reference

12 December 2020

Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

1 reference

12 December 2020

HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target

1 reference

12 December 2020

MDMX: from bench to bedside

1 reference

12 December 2020

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

1 reference

12 December 2020

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

1 reference

12 December 2020

Surfing the p53 network

1 reference

12 December 2020

Identifiers

DOI

10.1111/CAS.12008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22937789%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference