(Q84928158)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

TCF7L2 promotes beta cell regeneration in human and mouse pancreas (English)

1 reference

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12 February 2020

5

1 reference

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12 February 2020

K Maedler

7

0 references

author name string

L Shu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K Zien

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

G Gutjahr

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

J Oberholzer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

J Kerr-Conte

6

1 reference

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12 February 2020

publication date

4 September 2012

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12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

12

1 reference

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12 February 2020

page(s)

3296-3307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22945304%20AND%20SRC:MED&resulttype=core&format=json

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass

12 February 2020

cites work

1 reference

12 December 2020

Pancreatic β-cells are generated by neogenesis from non-β-cells after birth

1 reference

12 December 2020

Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice

1 reference

12 December 2020

β-cell regeneration: the pancreatic intrinsic faculty.

1 reference

12 December 2020

Mechanisms of KGF mediated signaling in pancreatic duct cell proliferation and differentiation

1 reference

12 December 2020

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

12 December 2020

beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma.

1 reference

12 December 2020

The antiinflammatory cytokine interleukin-1 receptor antagonist protects from high-fat diet-induced hyperglycemia

1 reference

12 December 2020

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

1 reference

12 December 2020

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

1 reference

12 December 2020

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

1 reference

12 December 2020

Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters

1 reference

12 December 2020

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

1 reference

12 December 2020

Intermediate endocrine-acinar pancreatic cells in duct ligation conditions.

1 reference

12 December 2020

Pancreatic duct replication is increased with obesity and type 2 diabetes in humans

1 reference

12 December 2020

Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival

1 reference

12 December 2020

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice.

1 reference

12 December 2020

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.

1 reference

12 December 2020

RETRACTED: Transcription factor 7-like 2 regulates beta-cell survival and function in human pancreatic islets

1 reference

12 December 2020

Cdk4 regulates recruitment of quiescent beta-cells and ductal epithelial progenitors to reconstitute beta-cell mass

1 reference

12 December 2020

Blockade of JAK2 activity suppressed accumulation of β-catenin in leukemic cells

1 reference

12 December 2020

Transdifferentiation of pancreatic ductal cells to endocrine β-cells

1 reference

12 December 2020

Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice

1 reference

12 December 2020

Ngn3 expression during postnatal in vitro beta cell neogenesis induced by the JAK/STAT pathway

1 reference

12 December 2020

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic beta-cells

1 reference

12 December 2020

Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration

1 reference

12 December 2020

TCF7L2 splice variants have distinct effects on beta-cell turnover and function

1 reference

12 December 2020

Tissue-specific alternative splicing of TCF7L2.

1 reference

12 December 2020

Neonatal growth and regeneration of beta-cells are regulated by the Wnt/beta-catenin signaling in normal and diabetic rats.

1 reference

12 December 2020

New sources of pancreatic beta-cells

1 reference

12 December 2020

Transforming growth factor‐β induces epithelial to mesenchymal transition and suppresses the proliferation and transdifferentiation of cultured human pancreatic duct cells

1 reference

12 December 2020

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

1 reference

12 December 2020

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets

1 reference

12 December 2020

Wnt signaling regulates pancreatic beta cell proliferation

1 reference

12 December 2020

Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization

1 reference

12 December 2020

Expression of Reg and cytokeratin 20 during ductal cell differentiation and proliferation in a mouse model of autoimmune diabetes.

1 reference

12 December 2020

The biology of incretin hormones

1 reference

12 December 2020

Assignment of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3

1 reference

12 December 2020

Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans

1 reference

12 December 2020

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

1 reference

12 December 2020

CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

1 reference

12 December 2020

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

1 reference

12 December 2020

Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes

1 reference

12 December 2020

Wnt signaling: relevance to beta-cell biology and diabetes

1 reference

12 December 2020

Postconditioning inhibits myocardial apoptosis during prolonged reperfusion via a JAK2-STAT3-Bcl-2 pathway

1 reference

12 December 2020