(Q84945701)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Activation of regulatory T cells instigates functional down-regulation of cytotoxic T lymphocytes in human breast cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Chao-Hsu Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Wen-Hong Kuo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Wen-Chun Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Su-Cheng Huang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

King-Jen Chang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

publication date

1 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

number of pages

9

1 reference

inferred from page(s)

published in

Immunologic Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

71-79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21918886%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12026-011-8242-x

12 February 2020

exact match

0 references

cites work

Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance

1 reference

12 December 2020

Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells

1 reference

12 December 2020

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

1 reference

12 December 2020

Decreased tumor surveillance in perforin-deficient mice

1 reference

12 December 2020

A novel role of metalloproteinase in cancer-mediated immunosuppression.

1 reference

12 December 2020

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

1 reference

12 December 2020

Cytokine regulation networks in the cancer microenvironment

1 reference

12 December 2020

Perforin deficiency attenuates inflammation and tumor growth in colitis-associated cancer.

1 reference

12 December 2020

Cell death mechanisms induced by cytotoxic lymphocytes

1 reference

12 December 2020

Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma

1 reference

12 December 2020

The significance of Treg cells in defective tumor immunity

1 reference

12 December 2020

Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune response in pancreas cancer-bearing mice

1 reference

12 December 2020

Predominant Th2/Tc2 Polarity of Tumor-Infiltrating Lymphocytes in Human Cervical Cancer

1 reference

12 December 2020

CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis

1 reference

12 December 2020

Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients?

1 reference

12 December 2020

Human T regulatory cells can use the perforin pathway to cause autologous target cell death

1 reference

12 December 2020

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

1 reference

12 December 2020

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

1 reference

12 December 2020

How regulatory T cells work

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12 December 2020

Tumor-infiltrating Foxp3-CD4+CD25+ T cells predict poor survival in renal cell carcinoma.

1 reference

12 December 2020

Host perforin reduces tumor number but does not increase survival in oncogene-driven mammary adenocarcinoma.

1 reference

12 December 2020

Up-regulation of Inhibitory Natural Killer Receptors CD94/NKG2A with Suppressed Intracellular Perforin Expression of Tumor-Infiltrating CD8+T Lymphocytes in Human Cervical Carcinoma

1 reference

12 December 2020

Reversed CD4/CD8 ratios of tumor-infiltrating lymphocytes are correlated with the progression of human cervical carcinoma.

1 reference

12 December 2020

Functional significance of the perforin/granzyme cell death pathway

1 reference

12 December 2020

Breast cancer and the immune system

1 reference

12 December 2020

Control of regulatory T cell development by the transcription factor Foxp3

1 reference

12 December 2020

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

1 reference

12 December 2020

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

12 December 2020

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

1 reference

12 December 2020

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

1 reference

12 December 2020

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

1 reference

12 December 2020

Bispecific antibody-mediated immunotherapy of the BCL1 lymphoma: increased efficacy with multiple injections and CD28-induced costimulation

1 reference

12 December 2020

Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

1 reference

12 December 2020

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

1 reference

12 December 2020

Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

1 reference

12 December 2020

Cutting edge: the related molecules CD28 and inducible costimulator deliver both unique and complementary signals required for optimal T cell activation

1 reference

12 December 2020

Regulatory T cells and infection: a dangerous necessity

1 reference

12 December 2020

Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma

1 reference

12 December 2020

A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

1 reference

12 December 2020

Positive and negative influences of regulatory T cells on tumour immunity.

1 reference

12 December 2020