(Q85194197)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23069659%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Ionizing radiation induces a dramatic persistence of p53 protein accumulation and DNA damage signaling in mutant p53 zebrafish (English)

1 reference

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15 February 2020

author name string

L Guo

1

1 reference

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15 February 2020

H P Liew

2

1 reference

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15 February 2020

S Camus

3

1 reference

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15 February 2020

A M Goh

4

1 reference

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15 February 2020

L L Chee

5

1 reference

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15 February 2020

D P Lunny

6

1 reference

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15 February 2020

E B Lane

7

1 reference

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15 February 2020

D P Lane

8

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15 February 2020

publication date

15 October 2012

1 reference

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15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23069659%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

32

1 reference

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15 February 2020

issue

34

1 reference

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15 February 2020

page(s)

4009-4016

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https://scigraph.springernature.com/pub.10.1038/onc.2012.409

15 February 2020

exact match

0 references

cites work

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Increased expression of mutant forms of p53 oncogene in primary lung cancer

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Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

31 March 2020

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p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

31 March 2020

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The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

31 March 2020

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

31 March 2020

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Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

31 March 2020

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Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function?

31 March 2020

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Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

31 March 2020

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Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

31 March 2020

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mdm2 expression is induced by wild type p53 activity

31 March 2020

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MDM2 and p53: a question of balance

31 March 2020

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tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

31 March 2020

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Detection of the p53 response in zebrafish embryos using new monoclonal antibodies

31 March 2020

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Detection of the 113p53 protein isoform: a p53-induced protein that feeds back on the p53 pathway to modulate the p53 response in zebrafish.

31 March 2020

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

31 March 2020

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p53 regulation: teamwork between RING domains of Mdm2 and MdmX.

31 March 2020

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MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination

31 March 2020

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

31 March 2020

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Mechanism of ubiquitylation by dimeric RING ligase RNF4

31 March 2020

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Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

31 March 2020

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Turning the RING domain protein MdmX into an active ubiquitin-protein ligase

31 March 2020

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p53 activation by knockdown technologies

31 March 2020

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Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

31 March 2020

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Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

31 March 2020

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Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells

31 March 2020

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

31 March 2020

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Mechanism-specific signatures for small-molecule p53 activators

31 March 2020

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Multiple stress signals activate mutant p53 in vivo

31 March 2020

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Zebrafish have a competent p53-dependent nucleotide excision repair pathway to resolve ultraviolet B-induced DNA damage in the skin

31 March 2020

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

31 March 2020

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p53 ubiquitination: Mdm2 and beyond

31 March 2020

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Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

31 March 2020

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Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability

31 March 2020

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The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo

31 March 2020

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An oncogene-induced DNA damage model for cancer development

31 March 2020

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