(Q85739124)

English

Regulation of MLH1 mRNA and protein expression by promoter methylation in primary colorectal cancer: a descriptive and prognostic cancer marker study

scientific article published on 12 September 2013

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027018%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Regulation of MLH1 mRNA and protein expression by promoter methylation in primary colorectal cancer: a descriptive and prognostic cancer marker study (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027018%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

Lars Henrik Jensen

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24027018%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Anders Jakobsen

8

1 reference

Europe PubMed Central

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21 February 2020

author name string

Anders Aamann Rasmussen

2

1 reference

Europe PubMed Central

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21 February 2020

Lene Byriel

3

1 reference

Europe PubMed Central

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21 February 2020

Hidekazu Kuramochi

4

1 reference

Europe PubMed Central

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21 February 2020

Dorthe Gylling Crüger

5

1 reference

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21 February 2020

Jan Lindebjerg

6

1 reference

Europe PubMed Central

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21 February 2020

Peter V Danenberg

7

1 reference

Europe PubMed Central

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21 February 2020

Kathleen Danenberg

9

1 reference

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21 February 2020

publication date

12 September 2013

1 reference

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21 February 2020

Cellular Oncology

1 reference

Europe PubMed Central

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21 February 2020

36

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21 February 2020

5

1 reference

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21 February 2020

411-419

1 reference

Europe PubMed Central

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21 February 2020

https://scigraph.springernature.com/pub.10.1007/s13402-013-0148-2

0 references

MMR gene expression pattern in sporadic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation analysis of MLH1 improves the selection of patients for genetic testing in Lynch syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the hMLH1 gene is a possible predictor for the clinical response to 5-fluorouracil after a surgical resection in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of aberrantly methylated hMLH1 promoter DNA in the serum of patients with microsatellite unstable colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of hMLH1 promoter correlates with the gene silencing with a region-specific manner in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to 5-fluorouracil of orthotopically xenografted human colon cancers with a microsatellite instability: influence of P53 status

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression of the mismatch repair gene MSH2 in primary colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvement of the methylation specific PCR technical conditions for the detection of p16 promoter hypermethylation in small amounts of tumor DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clues to the pathogenesis of familial colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of colorectal cancer based on correlation of clinical, morphological and molecular features

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of hypermethylation of the hMLH1 promoter region in HNPCC versus MSI+ sporadic colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology from bench-to-bedside - which colorectal cancer patients should be referred for genetic counselling and risk assessment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular screening for Lynch syndrome: from bench to bedside

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mismatch repair proficiency and in vitro response to 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA mismatch repair status and colon cancer recurrence and survival in clinical trials of 5-fluorouracil-based adjuvant therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG islands and the regulation of transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced mRNA expression in paraffin-embedded tissue identifies MLH1- and MSH2-deficient colorectal tumours and potential mutation carriers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive Screening for Lynch Syndrome: Who Can Be the Driving Force in Daily Clinical Practice?

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategy in clinical practice for classification of unselected colorectal tumours based on mismatch repair deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further evidence for heritability of an epimutation in one of 12 cases with MLH1 promoter methylation in blood cells clinically displaying HNPCC

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic review of microsatellite instability and colorectal cancer prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24027018

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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