(Q86199528)

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Chemokines in cancer

scientific article published on 01 December 2014

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

Europe PubMed Central

Chemokines in cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Melvyn T Chow

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Andrew D Luster

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

publication date

1 December 2014

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Cancer Immunology Research

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1125-1131

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Breast cancer lung metastasis requires expression of chemokine receptor CCR4 and regulatory T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR4 regulates growth of both primary and metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CXCR3 targeting chemokine CXCL11 has potent antitumor activity in vivo involving attraction of CD8+ T lymphocytes but not inhibition of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of C-C chemokine receptor 5 suppresses tumor development via inactivation of NF-κB and upregulation of IL-1Ra in melanoma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural killer cell accumulation in tumors is dependent on IFN-gamma and CXCR3 ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCL10 Can Inhibit Endothelial Cell Proliferation Independently of CXCR3

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinated regulation of myeloid cells by tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The many roles of chemokines and chemokine receptors in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines and chemokine receptors: positioning cells for host defense and immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of chemokines in melanoma tumor growth and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural innate and adaptive immunity to cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR3+ T regulatory cells selectively accumulate in human ovarian carcinomas to limit type I immunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXC chemokines in angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallmarks of Cancer: The Next Generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of CXCL12 and CXCR4 in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive cell transfer: a clinical path to effective cancer immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maximal T cell-mediated antitumor responses rely upon CCR5 expression in both CD4(+) and CD8(+) T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR3 in T cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory chemokine CCL5 and cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CXCL1 paracrine network links cancer chemoresistance and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of chemokine receptors in breast cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenic cell death in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeostatic chemokine receptors and organ-specific metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody therapy of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metastasis: from dissemination to organ-specific colonization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumorigenesis and the angiogenic switch

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemokine system in diverse forms of macrophage activation and polarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immune contexture in human tumours: impact on clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer and the chemokine network

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine receptor CXCR4-mediated transformation of mammary epithelial cells by enhancing multiple RTKs expression and deregulation of the p53/MDM2 axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells: mechanisms of differentiation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of T-cell chemotaxis by programmed death-ligand 1 (PD-L1) in dry eye-associated corneal inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer cell-derived lymphotoxin mediates reciprocal tumour-stromal interactions in human ovarian cancer by inducing CXCL11 in fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming hurdles in developing successful drugs targeting chemokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage diversity enhances tumor progression and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The elevated level of CXCR4 is correlated with nodal metastasis of human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CXCR3 deficiency prolongs Th1-type contact hypersensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25480554

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/2326-6066.CIR-14-0160

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25480554%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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