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non-structural protein 5 [SARS-CoV-2]
protein of SARS-CoV-2
SARS-CoV-2 main protease
3CLPRO
3CLp
Mpro
Nsp5
3C-like proteinase
nsp5
In more languages
default for all languages
No label defined
No description defined
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Statements
instance of
protein
0 references
protein fragment
of
orf1ab polyprotein [SARS-Cov 2]
1 reference
reference URL
https://covid-19.uniprot.org/uniprotkb/P0DTD1
retrieved
10 April 2020
subclass of
SARS coronavirus main proteinase
0 references
protein fragment
of
orf1ab polyprotein [SARS-Cov 2]
0 references
short name
nsp5
(English)
0 references
found in taxon
SARS-CoV-2
1 reference
reference URL
https://covid-19.uniprot.org/uniprotkb/P0DTD1
retrieved
10 April 2020
physically interacts with
histone deacetylase 2
determination method
Affinity Capture-MS
2 references
stated in
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
TRNA methyltransferase 1
determination method
Affinity Capture-MS
2 references
stated in
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
glutathione peroxidase 1
determination method
Affinity Capture-MS
1 reference
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae), isoform CRA_c
determination method
Affinity Capture-MS
1 reference
reference URL
https://thebiogrid.org/news/227
retrieved
19 April 2020
stated in
BioGRID
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing
Identifiers
RefSeq protein ID
YP_009725301
1 reference
reference URL
https://www.ncbi.nlm.nih.gov/protein/YP_009725301
retrieved
23 April 2020
UniProt protein ID
P0DTC1-PRO_0000449639
1 reference
reference URL
https://www.uniprot.org/uniprot/P0DTC1
P0DTD1-PRO_0000449623
1 reference
reference URL
https://www.uniprot.org/uniprot/P0DTD1
Guide to Pharmacology Target ID
3111
1 reference
reference URL
https://www.guidetopharmacology.org/coronavirus.jsp
retrieved
22 April 2020
PDB structure ID
6M03
1 reference
stated in
The crystal structure of COVID-19 main protease in apo form
6Y2E
1 reference
stated in
Crystal structure of the free enzyme of the SARS-CoV-2 (2019-nCoV) main protease
6Y84
1 reference
stated in
COVID-19 main protease with unliganded active site (2019-nCoV, coronavirus disease 2019, SARS-CoV-2)
5R81
1 reference
stated in
PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z1367324110
5R82
1 reference
stated in
PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z219104216
5R83
1 reference
stated in
PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z44592329
6Y2F
1 reference
stated in
Crystal structure (monoclinic form) of the complex resulting from the reaction between SARS-CoV-2 (2019-nCoV) main protease and tert-butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxoprop
6LU7
1 reference
stated in
Chemistry and Biology of SARS-CoV-2
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