(Q88622542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29744849%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Using Molecular Tweezers to Remodel Abnormal Protein Self-Assembly and Inhibit the Toxicity of Amyloidogenic Proteins (English)

1 reference

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26 March 2020

author name string

Ravinder Malik

1

1 reference

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26 March 2020

Jing Di

2

1 reference

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26 March 2020

Gayatri Nair

3

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26 March 2020

Aida Attar

4

1 reference

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26 March 2020

Karen Taylor

5

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26 March 2020

Edmond Teng

6

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26 March 2020

Frank-Gerrit Klärner

7

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26 March 2020

Thomas Schrader

8

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26 March 2020

Gal Bitan

9

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26 March 2020

publication date

1 January 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29744849%20AND%20SRC:MED&resulttype=core&format=json

Methods in Molecular Biology

26 March 2020

published in

1 reference

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26 March 2020

volume

1777

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26 March 2020

page(s)

369-386

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26 March 2020

1 reference

12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

1 reference

12 December 2020

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

12 December 2020

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

1 reference

12 December 2020

A molecular tweezer for lysine and arginine

1 reference

12 December 2020

Facile and efficient postsynthetic tritium labeling method catalyzed by Pd/C in HTO

1 reference

12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

12 December 2020

A transgenic rat model of Alzheimer's disease with extracellular Abeta deposition

1 reference

12 December 2020

Semen-derived amyloid fibrils drastically enhance HIV infection

1 reference

12 December 2020

The heat shock response modulates transthyretin deposition in the peripheral and autonomic nervous systems

1 reference

12 December 2020

Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disorders

1 reference

12 December 2020

Molecular clip and tweezer introduce new mechanisms of enzyme inhibition

1 reference

12 December 2020

Photo-induced cross-linking of unmodified proteins (PICUP) applied to amyloidogenic peptides.

1 reference

12 December 2020

Protein aggregation diseases: pathogenicity and therapeutic perspectives

1 reference

12 December 2020

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

1 reference

12 December 2020

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

1 reference

12 December 2020

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

1 reference

12 December 2020

Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

1 reference

12 December 2020

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.

1 reference

12 December 2020

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.

1 reference

12 December 2020

Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01

1 reference

12 December 2020

Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers

1 reference

12 December 2020

Molecular tweezers modulate 14-3-3 protein-protein interactions

1 reference

12 December 2020

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

1 reference

12 December 2020

Thinking laterally about neurodegenerative proteinopathies

1 reference

12 December 2020

Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases

1 reference

12 December 2020

Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal models

1 reference

12 December 2020

Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins.

1 reference

12 December 2020

Molecular Tweezers Targeting Transthyretin Amyloidosis

1 reference

12 December 2020

Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease

1 reference

12 December 2020

Molecular basis for preventing α-synuclein aggregation by a molecular tweezer.

1 reference

12 December 2020

Safety and pharmacological characterization of the molecular tweezer CLR01 - a broad-spectrum inhibitor of amyloid proteins' toxicity

1 reference

12 December 2020

Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia.

1 reference

12 December 2020

Current and future treatment of amyloid neuropathies.

1 reference

12 December 2020

Amyloid β-Protein Assembly: The Effect of Molecular Tweezers CLR01 and CLR03

1 reference

12 December 2020

Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism

1 reference

12 December 2020

The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity

1 reference

12 December 2020

A molecular tweezer antagonizes seminal amyloids and HIV infection.

1 reference

12 December 2020

Toxicity inhibitors protect lipid membranes from disruption by Aβ42.

1 reference

12 December 2020

Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos

1 reference

12 December 2020

Molecular tweezers for lysine and arginine - powerful inhibitors of pathologic protein aggregation

1 reference

12 December 2020

10.1007/978-1-4939-7811-3_24

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29744849%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29744849%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

29744849

1 reference