(Q89403466)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29969362%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

Targeting Cdc42 with the anticancer compound MBQ-167 inhibits cell polarity and growth in the budding yeast S. cerevisiae (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29969362%20AND%20SRC:MED&resulttype=core&format=json

Michael John Rivera-Robles

4 April 2020

author

1

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4 April 2020

author name string

Julia Medina-Velázquez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29969362%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

Gabriela M Asencio-Torres

3

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4 April 2020

Sahily González-Crespo

4

1 reference

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4 April 2020

Brian C Rymond

5

1 reference

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4 April 2020

José Rodríguez-Medina

6

1 reference

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4 April 2020

Suranganie Dharmawardhane

7

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4 April 2020

publication date

29 July 2018

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4 April 2020

published in

Small GTPases (journal)

1 reference

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4 April 2020

page(s)

1-11

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Development of cell polarity in budding yeast

4 April 2020

cites work

1 reference

12 December 2020

Staining of bud scars and other cell wall chitin with calcofluor

1 reference

12 December 2020

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity

1 reference

12 December 2020

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Cell polarity in yeast

1 reference

12 December 2020

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity

1 reference

12 December 2020

The statistics of synergism

1 reference

12 December 2020

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity

1 reference

12 December 2020

Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast

1 reference

12 December 2020

Multiple roles for Cdc42 in cell regulation

1 reference

12 December 2020

Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

1 reference

12 December 2020

Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p

1 reference

12 December 2020

Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.

1 reference

12 December 2020

Singularity in budding: a role for the evolutionarily conserved small GTPase Cdc42p

1 reference

12 December 2020

Cancer therapeutics in yeast

1 reference

12 December 2020

Cdc42--the centre of polarity

1 reference

12 December 2020

Exploration of essential gene functions via titratable promoter alleles

1 reference

12 December 2020

Rho GTPases: biochemistry and biology

1 reference

12 December 2020

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells

1 reference

12 December 2020

Biochemical and genetic analysis of the yeast proteome with a movable ORF collection

1 reference

12 December 2020

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases

1 reference

12 December 2020

Systems biology and combination therapy in the quest for clinical efficacy.

1 reference

12 December 2020

Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes

1 reference

12 December 2020

Central roles of small GTPases in the development of cell polarity in yeast and beyond

1 reference

12 December 2020

Dosage rescue by UBC4 restores cell wall integrity in Saccharomyces cerevisiae lacking the myosin type II gene MYO1.

1 reference

12 December 2020

Yeast on drugs: Saccharomyces cerevisiae as a tool for anticancer drug research.

1 reference

12 December 2020

High-throughput and sensitive assay to measure yeast cell growth: a bench protocol for testing genotoxic agents

1 reference

12 December 2020

A flip-flop switch in polarity signaling.

1 reference

12 December 2020

A method for high-throughput quantitative analysis of yeast chronological life span

1 reference

12 December 2020

Symmetry breaking in the life cycle of the budding yeast

1 reference

12 December 2020

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

1 reference

12 December 2020

Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase

1 reference

12 December 2020

Cell polarization and cytokinesis in budding yeast

1 reference

12 December 2020

Inhibition of Cdc42 during mitotic exit is required for cytokinesis

1 reference

12 December 2020

Growth rates made easy.

1 reference

12 December 2020

Cell polarization in budding and fission yeasts

1 reference

12 December 2020

Development of EHop-016: a small molecule inhibitor of Rac.

1 reference

12 December 2020

The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model

1 reference

12 December 2020

Pharmacokinetics of Rac inhibitor EHop-016 in mice by ultra-performance liquid chromatography tandem mass spectrometry

1 reference

12 December 2020

Protocols and programs for high-throughput growth and aging phenotyping in yeast

1 reference

12 December 2020

Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity

1 reference

12 December 2020

Analysis of drug combinations: current methodological landscape

1 reference

12 December 2020

Polarity establishment requires localized activation of Cdc42.

1 reference

12 December 2020

High-Speed Super-Resolution Imaging of Live Fission Yeast Cells.

1 reference

12 December 2020

Functional genomics to uncover drug mechanism of action.

1 reference

12 December 2020

Structural Mechanisms and Drug Discovery Prospects of Rho GTPases

1 reference

12 December 2020

Rho GTPases: Regulation and roles in cancer cell biology

1 reference

12 December 2020

Many roads to symmetry breaking: molecular mechanisms and theoretical models of yeast cell polarity

1 reference

12 December 2020

Polarity establishment by Cdc42: Key roles for positive feedback and differential mobility.

1 reference

12 December 2020

Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.

1 reference

12 December 2020

Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras-Related Cancers

1 reference

12 December 2020

Emerging and evolving concepts in gene essentiality.

1 reference

12 December 2020

10.1080/21541248.2018.1495008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29969362%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference