(Q89748900)

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MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification

scientific article published on 28 December 2017

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

4

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8 April 2020

Brian J. Abraham

5

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8 April 2020

8

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8 April 2020

Richard A. Young

13

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8 April 2020

author name string

Mark W Zimmerman

1

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8 April 2020

Yu Liu

2

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8 April 2020

Shuning He

3

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8 April 2020

John Easton

6

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8 April 2020

Ying Shao

7

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8 April 2020

Shizhen Zhu

9

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8 April 2020

Xiaoling Zhang

10

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8 April 2020

Zhaodong Li

11

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8 April 2020

Nina Weichert-Leahey

12

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8 April 2020

Jinghui Zhang

14

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8 April 2020

A Thomas Look

15

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8 April 2020

publication date

28 December 2017

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8 April 2020

Cancer Discovery

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

8

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Europe PubMed Central

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8 April 2020

3

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Europe PubMed Central

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8 April 2020

320-335

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5856009/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5856009/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Special pattern of widespread neuroblastoma with a favourable prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation and maturation of zebrafish dorsal root and sympathetic ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditional deletion of Hand2 reveals critical functions in neurogenesis and cell type-specific gene expression for development of neural crest-derived noradrenergic sympathetic ganglion neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reflecting on 25 years with MYC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forcing cells to change lineages

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myc proteins as therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated ALK collaborates with MYCN in neuroblastoma pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topological domains in mammalian genomes identified by analysis of chromatin interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 8q24 gene desert: an oasis of non-coding transcriptional activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional amplification in tumor cells with elevated c-Myc.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic landscape of high-risk neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Master transcription factors and mediator establish super-enhancers at key cell identity genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of tumor oncogenes by disruption of super-enhancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct neuroblastoma-associated alterations of PHOX2B impair sympathetic neuronal differentiation in zebrafish models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroblastoma of undifferentiated subtype, prognostic significance of prominent nucleolar formation, and MYC/MYCN protein expression: a report from the Children's Oncology Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inferring tumour purity and stromal and immune cell admixture from expression data

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Super-enhancers in the control of cell identity and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HTSeq--a Python framework to work with high-throughput sequencing data

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Cancer Genomics Hub (CGHub): overcoming cancer through the power of torrential data

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring genomic alteration in pediatric cancer using ProteinPaint

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studying the peripheral sympathetic nervous system and neuroblastoma in zebrafish.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulated Neighborhoods: Structural and Functional Units of Mammalian Gene Control

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small genomic insertions form enhancers that misregulate oncogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Phase Separation Model for Transcriptional Control.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroblastoma is composed of two super-enhancer-associated differentiation states.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

11q deletion in neuroblastoma: a review of biological and clinical implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29284669

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/2159-8290.CD-17-0993

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29284669%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

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