(Q34429918)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor (English)

1 reference

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10 March 2020

4

1 reference

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10 March 2020

Richard A. Young

23

1 reference

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10 March 2020

1

Nicholas Kwiatkowski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

24

Nathanael S Gray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

14

Takaomi Sanda

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

17

Thomas Look

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

author name string

Tinghu Zhang

2

1 reference

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10 March 2020

Peter B Rahl

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Jessica Reddy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Scott B Ficarro

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Anahita Dastur

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Arnaud Amzallag

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Sridhar Ramaswamy

9

1 reference

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10 March 2020

Bethany Tesar

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Catherine E Jenkins

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Nancy M Hannett

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Douglas McMillin

13

1 reference

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10 March 2020

Taebo Sim

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Nam Doo Kim

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Constantine S Mitsiades

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Andrew P Weng

19

1 reference

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10 March 2020

Jennifer R Brown

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Cyril H Benes

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Jarrod A Marto

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

language of work or name

English

0 references

publication date

22 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

616-620

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

issue

7511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature13393

10 March 2020

exact match

0 references

cites work

Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Super-enhancers in the control of cell identity and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Pause, play, repeat: CDKs push RNAP II's buttons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Selective inhibition of tumor oncogenes by disruption of super-enhancers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Revisiting global gene expression analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Systematic identification of genomic markers of drug sensitivity in cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Perspectives on the discovery of small-molecule modulators for epigenetic processes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

c-Myc regulates transcriptional pause release

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Inhibition of transcription factors with small organic molecules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Mechanisms of transcription factor deregulation in lymphoid cell transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Functional interrogation of the kinome using nucleotide acyl phosphates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Human cyclin-dependent kinase-activating kinase exists in three distinct complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

A cyclin associated with the CDK-activating kinase MO15

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Association of Cdk-activating kinase subunits with transcription factor TFIIH

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Cdk-activating kinase complex is a component of human transcription factor TFIIH

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4244910

P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13393

Modulation of TFIIH-associated kinase activity by complex formation and its relationship with CTD phosphorylation of RNA polymerase II

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043025

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13393

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043025%20AND%20SRC:MED&resulttype=core&format=json