(Q90436647)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

title

Astrocytes and microglia: Models and tools (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

Shane A Liddelow

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

publication date

12 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

14 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

volume

216

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

page(s)

71-83

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

Determination of glial fibrillary acidic protein (GFAP) in human brain tumors

14 April 2020

cites work

1 reference

12 December 2020

The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration

1 reference

12 December 2020

An acidic protein isolated from fibrous astrocytes

1 reference

12 December 2020

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

1 reference

12 December 2020

Glial fibrillary acidic protein (GFAP) in ependymal cells during development. An immunocytochemical study

1 reference

12 December 2020

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1 reference

12 December 2020

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared

1 reference

12 December 2020

Mice lacking vimentin develop and reproduce without an obvious phenotype

1 reference

12 December 2020

GFAP promoter directs astrocyte-specific expression in transgenic mice.

1 reference

12 December 2020

Phagocytozing ameboid microglial cells studied in a mouse corpus callosum slice preparation

1 reference

12 December 2020

Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination

1 reference

12 December 2020

Synaptic efficacy enhanced by glial cells in vitro.

1 reference

12 December 2020

Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion

1 reference

12 December 2020

Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1

1 reference

12 December 2020

Abnormal astrocyte development and neuronal death in mice lacking the epidermal growth factor receptor

1 reference

12 December 2020

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

1 reference

12 December 2020

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

1 reference

12 December 2020

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

1 reference

12 December 2020

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

1 reference

12 December 2020

hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo.

1 reference

12 December 2020

CNS synaptogenesis promoted by glia-derived cholesterol

1 reference

12 December 2020

Inactivation of the F4/80 glycoprotein in the mouse germ line

1 reference

12 December 2020

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

1 reference

12 December 2020

GDNF and TGF-beta1 promote cell survival in serum-free cultures of primary rat microglia

1 reference

12 December 2020

Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin.

1 reference

12 December 2020

Ephrin-B2 and EphB2 regulation of astrocyte-meningeal fibroblast interactions in response to spinal cord lesions in adult rats.

1 reference

12 December 2020

Diverse microglial motility behaviors during clearance of dead cells in hippocampal slices

1 reference

12 December 2020

Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.

1 reference

12 December 2020

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

1 reference

12 December 2020

Fluorescent proteins expressed in mouse transgenic lines mark subsets of glia, neurons, macrophages, and dendritic cells for vital examination.

1 reference

12 December 2020

Expression specificity of GFAP transgenes

1 reference

12 December 2020

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

1 reference

12 December 2020

Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis

1 reference

12 December 2020

Targeted expression of Cre recombinase in macrophages and osteoclasts in transgenic mice.

1 reference

12 December 2020

Visualization of microglia in living tissues using Iba1-EGFP transgenic mice

1 reference

12 December 2020

Bone marrow stromal cells increase astrocyte survival via upregulation of phosphoinositide 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic f

1 reference

12 December 2020

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Early postnatal astroglial cells produce multilineage precursors and neural stem cells in vivo.

1 reference

12 December 2020

Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis.

1 reference

12 December 2020

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

1 reference

12 December 2020

Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord.

1 reference

12 December 2020

Monocyte/macrophage suppression in CD11b diphtheria toxin receptor transgenic mice differentially affects atherogenesis and established plaques

1 reference

12 December 2020

Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS.

1 reference

12 December 2020

Transgenic mice for conditional gene manipulation in astroglial cells.

1 reference

12 December 2020

Dynamic contribution of nestin-expressing stem cells to adult neurogenesis

1 reference

12 December 2020

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

1 reference

12 December 2020

GUDMAP: the genitourinary developmental molecular anatomy project

1 reference

12 December 2020

Intermediate progenitors in adult hippocampal neurogenesis: Tbr2 expression and coordinate regulation of neuronal output

1 reference

12 December 2020

Selective ablation of proliferating astrocytes does not affect disease outcome in either acute or chronic models of motor neuron degeneration

1 reference

12 December 2020

Transgenic tools for analysis of the haematopoietic system: Knock-in CD45 reporter and deletor mice

1 reference

12 December 2020

The mystery and magic of glia: a perspective on their roles in health and disease

1 reference

12 December 2020

A translational profiling approach for the molecular characterization of CNS cell types

1 reference

12 December 2020

Application of a translational profiling approach for the comparative analysis of CNS cell types

1 reference

12 December 2020

Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris

1 reference

12 December 2020

Inducible transgenes under the control of the hCD68 promoter identifies mouse macrophages with a distribution that differs from the F4/80 - and CSF-1R-expressing populations

1 reference

12 December 2020

Molecular dissection of reactive astrogliosis and glial scar formation

1 reference

12 December 2020

Astrocytes: biology and pathology

1 reference

12 December 2020

Glial fibrillary acidic protein-expressing neural progenitors give rise to immature neurons via early intermediate progenitors expressing both glial fibrillary acidic protein and neuronal markers in the adult hippocampus

1 reference

12 December 2020

A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis

1 reference

12 December 2020

A mouse line expressing Sall1-driven inducible Cre recombinase in the kidney mesenchyme

1 reference

12 December 2020

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

1 reference

12 December 2020

Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice

1 reference

12 December 2020

NG2+ CNS glial progenitors remain committed to the oligodendrocyte lineage in postnatal life and following neurodegeneration.

1 reference

12 December 2020

The GUDMAP database--an online resource for genitourinary research

1 reference

12 December 2020

Synaptic pruning by microglia is necessary for normal brain development

1 reference

12 December 2020

Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC

1 reference

12 December 2020

Development of a method for the purification and culture of rodent astrocytes

1 reference

12 December 2020

Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation

1 reference

12 December 2020

Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2

1 reference

12 December 2020

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

1 reference

12 December 2020

Genomic analysis of reactive astrogliosis

1 reference

12 December 2020

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

1 reference

12 December 2020

A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease

1 reference

12 December 2020

Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors

1 reference

12 December 2020

Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation

1 reference

12 December 2020

Capture, crawl, cross: the T cell code to breach the blood-brain barriers

1 reference

12 December 2020

Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice

1 reference

12 December 2020

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

1 reference

12 December 2020

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration

1 reference

12 December 2020

Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity

1 reference

12 December 2020

HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis

1 reference

12 December 2020

Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

1 reference

12 December 2020

Microglia: scapegoat, saboteur, or something else?

1 reference

12 December 2020

'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation

1 reference

12 December 2020

A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies

1 reference

12 December 2020

Microglia, seen from the CX3CR1 angle

1 reference

12 December 2020

Aldh1L1 is expressed by postnatal neural stem cells in vivo

1 reference

12 December 2020

Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium

1 reference

12 December 2020

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

1 reference

12 December 2020

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

1 reference

12 December 2020

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

1 reference

12 December 2020

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor.

1 reference

12 December 2020

Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain.

1 reference

12 December 2020

Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP).

1 reference

12 December 2020

Astrocytic TGF-β signaling limits inflammation and reduces neuronal damage during central nervous system Toxoplasma infection

1 reference

12 December 2020

Non-mammalian model systems for studying neuro-immune interactions after spinal cord injury

1 reference

12 December 2020

Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.

1 reference

12 December 2020

Neuron-glia interactions through the Heartless FGF receptor signaling pathway mediate morphogenesis of Drosophila astrocytes

1 reference

12 December 2020

An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

1 reference

12 December 2020

BMP signaling in astrocytes downregulates EGFR to modulate survival and maturation

1 reference

12 December 2020

Astrocyte development and heterogeneity

1 reference

12 December 2020

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors.

1 reference

12 December 2020

Neuronal transgene expression in dominant-negative SNARE mice

1 reference

12 December 2020

Looks can be deceiving: reconsidering the evidence for gliotransmission

1 reference

12 December 2020

The Astrocyte: Powerhouse and Recycling Center

1 reference

12 December 2020

Glia Open Access Database (GOAD): A comprehensive gene expression encyclopedia of glia cells in health and disease.

1 reference

12 December 2020

Astrocyte regulation of blood flow in the brain

1 reference

12 December 2020

Immune attack: the role of inflammation in Alzheimer disease.

1 reference

12 December 2020

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

1 reference

12 December 2020

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

1 reference

12 December 2020

Elusive roles for reactive astrocytes in neurodegenerative diseases

1 reference

12 December 2020

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.

1 reference

12 December 2020

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

1 reference

12 December 2020

New tools for studying microglia in the mouse and human CNS.

1 reference

12 December 2020

Stable biomarker for plastic microglia

1 reference

12 December 2020

Astrocyte scar formation aids central nervous system axon regeneration

1 reference

12 December 2020

Inducible targeting of cDCs and their subsets in vivo

1 reference

12 December 2020

Origin, fate and dynamics of macrophages at central nervous system interfaces

1 reference

12 December 2020

Microglia replenished OHSC: A culture system to study in vivo like adult microglia.

1 reference

12 December 2020

A comparative transcriptomic analysis of astrocytes differentiation from human neural progenitor cells

1 reference

12 December 2020

Efficient derivation of microglia-like cells from human pluripotent stem cells

1 reference

12 December 2020

Sall1 is a transcriptional regulator defining microglia identity and function.

1 reference

12 December 2020

New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo.

1 reference

12 December 2020

Neurotoxic reactive astrocytes are induced by activated microglia

1 reference

12 December 2020

Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice

1 reference

12 December 2020

Anti-ACSA-2 defines a novel monoclonal antibody for prospective isolation of living neonatal and adult astrocytes.

1 reference

12 December 2020

An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody

1 reference

12 December 2020

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

1 reference

12 December 2020

iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases.

1 reference

12 December 2020

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures

1 reference

12 December 2020

Directed Differentiation of Human Pluripotent Stem Cells to Microglia

1 reference

12 December 2020

An environment-dependent transcriptional network specifies human microglia identity

1 reference

12 December 2020

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

1 reference

12 December 2020

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

1 reference

12 December 2020

Reactive Astrocytes: Production, Function, and Therapeutic Potential

1 reference

12 December 2020

Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

1 reference

12 December 2020

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

1 reference

12 December 2020

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells.

1 reference

12 December 2020

Detecting Activated Cell Populations Using Single-Cell RNA-Seq

1 reference

12 December 2020

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis.

1 reference

12 December 2020

Microglia and macrophages in brain homeostasis and disease

1 reference

12 December 2020

The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain

1 reference

12 December 2020

Detecting and Avoiding Problems When Using the Cre-lox System.

1 reference

12 December 2020

CRISPR interference-based specific and efficient gene inactivation in the brain.

1 reference

12 December 2020

Brain transcriptome databases: a user's guide.

1 reference

12 December 2020

Normal aging induces A1-like astrocyte reactivity.

1 reference

12 December 2020

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

1 reference

12 December 2020

The role of the microglial Cx3cr1 pathway in the post-natal maturation of retinal photoreceptors.

1 reference

12 December 2020

Microglial control of astrocytes in response to microbial metabolites.

1 reference

12 December 2020

A Combination of Ontogeny and CNS Environment Establishes Microglial Identity

1 reference

12 December 2020

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

1 reference

12 December 2020

Molecular Architecture of the Mouse Nervous System

1 reference

12 December 2020

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20180200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30541903%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

PubMed publication ID

30541903

1 reference