(Q909425)

English

Oncostatin M

mammalian protein found in Homo sapiens

oncostatin-M
OSM

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

OncostatinM Crystal Structure.rsh.png
832 × 753; 200 KB

0 references

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

cytokine activity

determination method

4 references

16 July 2018

Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13725&geneProductId=UniProtKB:P13725

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13725&geneProductId=UniProtKB:P13725

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13725&geneProductId=UniProtKB:P13725

determination method

16 July 2018

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13725&geneProductId=UniProtKB:P13725

determination method

oncostatin-M receptor binding

determination method

2 references

growth factor activity

determination method

1 reference

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

cytokine activity

determination method

5 references

8 April 2019

Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

oncostatin-M receptor binding

determination method

3 references

8 April 2019

Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

biological process

oncostatin-M-mediated signaling pathway

determination method

1 reference

16 July 2018

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13725&geneProductId=UniProtKB:P13725

determination method

positive regulation of peptidyl-serine phosphorylation

determination method

1 reference

8 April 2019

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

multicellular organism development

determination method

1 reference

8 April 2019

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

immune response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of acute inflammatory response

determination method

1 reference

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

regulation of growth

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

cell population proliferation

determination method

1 reference

1 January 2018

Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

negative regulation of hormone secretion

determination method

1 reference

8 April 2019

Inhibition of growth hormone-releasing factor production in mouse placenta by cytokines using gp130 as a signal transducer

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of cell division

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of MAPK cascade

determination method

1 reference

8 April 2019

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

negative regulation of cell population proliferation

determination method

1 reference

8 April 2019

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of tyrosine phosphorylation of STAT protein

determination method

1 reference

8 April 2019

CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of peptidyl-tyrosine phosphorylation

determination method

2 references

8 April 2019

Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor, and oncostatin M in mouse 3T3-L1 cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

8 April 2019

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

cytokine-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of phosphatidylinositol 3-kinase signaling

determination method

1 reference

8 April 2019

MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of inflammatory response

determination method

1 reference

8 April 2019

MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

positive regulation of protein kinase B signaling

determination method

1 reference

8 April 2019

MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

regulation of hematopoietic stem cell differentiation

determination method

1 reference

8 April 2019

Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13725

determination method

Identifiers

MeSH descriptor ID

subject named as

Oncostatin M

0 references

D12.644.276.374.562

0 references

D12.776.467.374.562

0 references

D23.529.374.562

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

0 references

Ensembl protein ID

ENSP00000215781

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000215781

ENSP00000383893

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000383893

ENSP00000384543

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000384543

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(7 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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