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Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance
scientific article published on 04 June 2019
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Europe PubMed Central
PMC publication ID
6631165
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
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30 April 2020
review article
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Europe PubMed Central
title
Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance
(English)
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stated in
Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 April 2020
author name string
Laura E Heller
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1
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Europe PubMed Central
PMC publication ID
6631165
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 April 2020
Paul D Roepe
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2
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Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
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30 April 2020
publication date
4 June 2019
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Europe PubMed Central
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6631165
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30 April 2020
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Tropical Medicine and Infectious Disease
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Europe PubMed Central
PMC publication ID
6631165
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
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30 April 2020
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4
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Europe PubMed Central
PMC publication ID
6631165
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30 April 2020
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2
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Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
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30 April 2020
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4 June 2019
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Artemisinin Resistance in Plasmodium falciparum Malaria
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Evidence of Artemisinin-Resistant Malaria in Western Cambodia
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Spinning disk confocal microscopy of live, intraerythrocytic malarial parasites. 1. Quantification of hemozoin development for drug sensitive versus resistant malaria
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Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia
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Antimalarial drug resistance
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Alkylation of heme by the antimalarial drug artemisinin
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From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs
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Alkylating capacity and reaction products of antimalarial trioxanes after activation by a heme model
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11 February 2021
Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3
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11 February 2021
Characterization of the Alkylation Product of Heme by the Antimalarial Drug Artemisinin We are grateful to the CNRS for financial support, and to the French Ministery of Education for a PhD grant to J.C. Dr. Yannick Coppel (LCC-CNRS) is gratefully a
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The structure of malaria pigment beta-haematin
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The fate of ferriprotorphyrin IX in malaria infected erythrocytes in conjunction with the mode of action of antimalarial drugs
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Effects of artemisinin derivatives on malaria transmissibility
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Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu).
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Plasmodium falciparum: in vitro studies of the pharmacodynamic properties of drugs used for the treatment of severe malaria
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Alkylation of human albumin by the antimalarial artemisinin
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
The interaction of artemisinin with malarial hemozoin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Alkylation of proteins by artemisinin. Effects of heme, pH, and drug structure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Effects of antimalarials and protease inhibitors on plasmodial hemozoin production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Qinghaosu (artemisinin): an antimalarial drug from China
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Malaria on the Thai-Burmese border: treatment of 5192 patients with mefloquine-sulfadoxine-pyrimethamine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Mefloquine-resistant falciparum malaria on the Thai-Burmese border
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Hemin-catalyzed decomposition of artemisinin (qinghaosu)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6631165
retrieved
11 February 2021
Identifiers
DOI
10.3390/TROPICALMED4020089
1 reference
stated in
Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 April 2020
PMC publication ID
6631165
1 reference
stated in
Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 April 2020
PubMed publication ID
31167396
1 reference
stated in
Europe PubMed Central
PMC publication ID
6631165
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31167396%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 April 2020
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