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Mechanism of 5' splice site transfer for human spliceosome activation
scientific article published on 11 April 2019
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Europe PubMed Central
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6525098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 May 2020
title
Mechanism of 5' splice site transfer for human spliceosome activation
(English)
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Europe PubMed Central
PMC publication ID
6525098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
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3 May 2020
author
Clement Charenton
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1
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Europe PubMed Central
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6525098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
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3 May 2020
Max E Wilkinson
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2
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Europe PubMed Central
PMC publication ID
6525098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
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3 May 2020
Kiyoshi Nagai
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3
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6525098
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3 May 2020
language of work or name
English
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publication date
11 April 2019
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6525098
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3 May 2020
published in
Science
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Europe PubMed Central
PMC publication ID
6525098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
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3 May 2020
volume
364
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Europe PubMed Central
PMC publication ID
6525098
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
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3 May 2020
issue
6438
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Europe PubMed Central
PMC publication ID
6525098
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3 May 2020
page(s)
362-367
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6525098
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3 May 2020
cites work
SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structural Basis of Nuclear pre-mRNA Splicing: Lessons from Yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
A human postcatalytic spliceosome structure reveals essential roles of metazoan factors for exon ligation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Molecular Mechanisms of pre-mRNA Splicing through Structural Biology of the Spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
New tools for automated high-resolution cryo-EM structure determination in RELION-3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structures of the human pre-catalytic spliceosome and its precursor spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
SNRP-27, the C. elegans homolog of the tri-snRNP 27K protein, has a role in 5' splice site positioning in the spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Prespliceosome structure provides insights into spliceosome assembly and regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structures of the fully assembled Saccharomyces cerevisiae spliceosome before activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structure of a pre-catalytic spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Molecular architecture of the human U4/U6.U5 tri-snRNP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Gctf: Real-time CTF determination and correction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
The architecture of the spliceosomal U4/U6.U5 tri-snRNP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
The Phyre2 web portal for protein modeling, prediction and analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
RNA catalyses nuclear pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Crystal structure of Prp8 reveals active site cavity of the spliceosome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structural basis for RNA-duplex recognition and unwinding by the DEAD-box helicase Mss116p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structural bioinformatics of the human spliceosomal proteome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
JLigand: a graphical tool for the CCP4 template-restraint library
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Features and development of Coot
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
PHENIX: a comprehensive Python-based system for macromolecular structure solution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
UCSF Chimera--a visualization system for exploratory research and analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
11 February 2021
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6525098
retrieved
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Identifiers
DOI
10.1126/SCIENCE.AAX3289
1 reference
stated in
Europe PubMed Central
PMC publication ID
6525098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 May 2020
PMC publication ID
6525098
1 reference
stated in
Europe PubMed Central
PMC publication ID
6525098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 May 2020
PubMed publication ID
30975767
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Europe PubMed Central
PMC publication ID
6525098
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30975767%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 May 2020
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