(Q43649668)

25 November 2017

title

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation (English)

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25 November 2017

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Reinhard Georg Lührmann

series ordinal

6

object named as

Reinhard Lührmann

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25 November 2017

3

Cindy L Will

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25 November 2017

5

Henning Urlaub

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25 November 2017

Marc Schneider

1

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25 November 2017

He-Hsuan Hsiao

series ordinal

2

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25 November 2017

Régis Giet

series ordinal

4

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25 November 2017

publication date

31 January 2010

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Nature Structural & Molecular Biology

25 November 2017

published in

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25 November 2017

volume

17

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25 November 2017

issue

2

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25 November 2017

page(s)

216-221

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https://scigraph.springernature.com/pub.10.1038/nsmb.1718

25 November 2017

exact match

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cites work

Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

1 reference

RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies

21 January 2018

1 reference

A human homolog of yeast pre-mRNA splicing gene, PRP31, underlies autosomal dominant retinitis pigmentosa on chromosome 19q13.4 (RP11)

21 January 2018

1 reference

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome

21 January 2018

1 reference

The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes

21 January 2018

1 reference

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome

21 January 2018

1 reference

SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome

21 January 2018

1 reference

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

21 January 2018

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Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.

21 January 2018

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Flipping the switch to an active spliceosome

21 January 2018

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SR proteins and splicing control

21 January 2018

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Sorting out the complexity of SR protein functions

21 January 2018

1 reference

Characterisation of human and murine snRNP proteins by two-dimensional gel electrophoresis and phosphopeptide analysis of U1-specific 70K protein variants

21 January 2018

1 reference

Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis

21 January 2018

1 reference

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

21 January 2018

1 reference

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors

21 January 2018

1 reference

Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

21 January 2018

1 reference

Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing

21 January 2018

1 reference

Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes

21 January 2018

1 reference

Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue

21 January 2018

1 reference

Cloning of human PRP4 reveals interaction with Clk1

21 January 2018

1 reference

Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor

21 January 2018

1 reference

Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.

21 January 2018

1 reference

PRP4 is a spindle assembly checkpoint protein required for MPS1, MAD1, and MAD2 localization to the kinetochores

21 January 2018

1 reference

The biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP.

21 January 2018

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The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions

21 January 2018

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Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae

21 January 2018

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The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP

21 January 2018

1 reference

Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP

21 January 2018

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Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

21 January 2018

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Isolation of an active step I spliceosome and composition of its RNP core.

21 January 2018

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An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

21 January 2018

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

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Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles

21 January 2018

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Organization of core spliceosomal components U5 snRNA loop I and U4/U6 Di-snRNP within U4/U6.U5 Tri-snRNP as revealed by electron cryomicroscopy

21 January 2018

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Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions

21 January 2018

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RNA structural requirements for the association of the spliceosomal hPrp31 protein with the U4 and U4atac small nuclear ribonucleoproteins

21 January 2018

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

21 January 2018

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Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns.

21 January 2018

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Thiophosphorylation of U1-70K protein inhibits pre-mRNA splicing

21 January 2018

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PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins

21 January 2018

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Multiple roles of the SR protein family in splicing regulation.

31 March 2020

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prp4 from Schizosaccharomyces pombe, a mutant deficient in pre-mRNA splicing isolated using genes containing artificial introns

31 March 2020

1 reference

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

31 March 2020

1 reference

12 December 2020

Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro

1 reference

12 December 2020

SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome

1 reference

12 December 2020

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution

1 reference

12 December 2020

The [U4/U6.U5] tri-snRNP-specific 27K protein is a novel SR protein that can be phosphorylated by the snRNP-associated protein kinase

1 reference

12 December 2020

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NSMB.1718

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25 November 2017

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