(Q93117054)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30989245%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

title

Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output (English)

1 reference

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3 May 2020

12

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3 May 2020

David I Yule

13

1 reference

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3 May 2020

Jan B. Parys

14

1 reference

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3 May 2020

Geert Bultynck

15

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3 May 2020

author name string

Hristina Ivanova

1

1 reference

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3 May 2020

Larry E Wagner

2

1 reference

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3 May 2020

Akihiko Tanimura

3

1 reference

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3 May 2020

Elien Vandermarliere

4

1 reference

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3 May 2020

Tomas Luyten

5

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3 May 2020

Kirsten Welkenhuyzen

6

1 reference

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3 May 2020

Kamil J Alzayady

7

1 reference

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3 May 2020

Liwei Wang

8

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3 May 2020

Kozo Hamada

9

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3 May 2020

Katsuhiko Mikoshiba

10

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3 May 2020

Humbert De Smedt

11

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3 May 2020

publication date

16 April 2019

1 reference

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Cellular and Molecular Life Sciences

3 May 2020

published in

1 reference

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3 May 2020

volume

76

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3 May 2020

issue

19

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3 May 2020

page(s)

3843-3859

1 reference

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Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate by the oocytes of Xenopus laevis.

3 May 2020

cites work

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

0 references

Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Regulation of the ryanodine receptor by anti-apoptotic Bcl-2 is independent of its BH3-domain-binding properties.

0 references

Mapping of the ATP-binding sites on inositol 1,4,5-trisphosphate receptor type 1 and type 3 homotetramers by controlled proteolysis and photoaffinity labeling.

0 references

Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

0 references

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

0 references

Trypsinized cerebellar inositol 1,4,5-trisphosphate receptor. Structural and functional coupling of cleaved ligand binding and channel domains.

0 references

Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.

0 references

Control of mitochondrial apoptosis by the Bcl-2 family

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor

0 references

Thimerosal stimulates Ca2+ flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction

0 references

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum

0 references

Gating machinery of InsP3R channels revealed by electron cryomicroscopy

0 references

Differential regulation of the InsP₃ receptor type-1 and -2 single channel properties by InsP₃, Ca²⁺ and ATP.

0 references

Measurement of intracellular Ca2+ release in intact and permeabilized cells using 45Ca2+

0 references

Breast cancer targeting through inhibition of the endoplasmic reticulum-based apoptosis regulator Nrh/BCL2L10.

0 references

Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor

0 references

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor

0 references

Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release.

0 references

IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography

0 references

Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.

0 references

Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor.

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Inhibition of Bax channel-forming activity by Bcl-2

0 references

The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP3 receptor channels

0 references

IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact

0 references

Bcl-2 binds to and inhibits ryanodine receptors.

0 references

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers

0 references

Adenophostins A and B: potent agonists of inositol-1,4,5-trisphosphate receptor produced by Penicillium brevicompactum. Structure elucidation

0 references

Bcl-2 regulation of the inositol 1,4,5-trisphosphate receptor and calcium signaling in normal and malignant lymphocytes: potential new target for cancer treatment

0 references

The trans-membrane domain of Bcl-2α, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition

0 references

The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis

0 references

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

3 May 2022

https://opencitations.net/index/coci/api/v1/references/10.1007/S00018-019-03091-8

Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation

0 references

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

0 references

Bcl-2 proteins and calcium signaling: complexity beneath the surface

0 references

Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling

0 references

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

0 references

The Bcl-2 homolog Nrz inhibits binding of IP3 to its receptor to control calcium signaling during zebrafish epiboly.

0 references

Involvement of the bcl-2 gene in human follicular lymphoma

0 references

FiberDock: a web server for flexible induced-fit backbone refinement in molecular docking

0 references

Identifiers

DOI

10.1007/S00018-019-03091-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30989245%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference