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Variations in Orf3a protein of SARS-CoV-2 alter its structure and function

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Variations in Orf3a protein of SARS-CoV-2 alter its structure and function (English)

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Viroporin 3a

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author name string

Gajendra Kumar Azad

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1

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Parimal Kumar Khan

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2

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English

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publication date

July 2021

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Biochemistry and Biophysics Reports

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volume

26

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page(s)

100933

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Exploiting heterogeneous sequence properties improves prediction of protein disorder.

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The open reading frame 3a protein of severe acute respiratory syndrome-associated coronavirus promotes membrane rearrangement and cell death

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The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells.

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Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

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SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far

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Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

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Genomic characterization of a novel SARS-CoV-2

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The EMBL-EBI search and sequence analysis tools APIs in 2019

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Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

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SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis

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Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure

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The outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): A review of the current global status

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Identification of twenty-five mutations in surface glycoprotein (Spike) of SARS-CoV-2 among Indian isolates and their impact on protein dynamics

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Non-synonymous Mutations of SARS-CoV-2 Leads Epitope Loss and Segregates its Variants

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ORF3a mutation associated higher mortality rate in SARS-CoV-2 infection

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SARS Accessory Proteins ORF3a and 9b and Their Functional Analysis

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3 July 2021

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10.1016/J.BBREP.2021.100933

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(Q107404382)

Variations in Orf3a protein of SARS-CoV-2 alter its structure and function

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