Wikidata

(Q1076248)

English

oleandomycin

chemical compound

In more languages

Statements

subclass of
macrolides
0 references
polyketide
0 references
chemical structure
Oleandomycin.png
712 × 605; 14 KB
0 references
mass
687.419376 dalton
1 reference
stated in
PubChem
PubChem CID
19822
language of work or name
English
title
oleandomycin (English)
retrieved
21 September 2016
chemical formula
C₃₅H₆₁NO₁₂
1 reference
stated in
PubChem
PubChem CID
19822
language of work or name
English
title
oleandomycin (English)
retrieved
21 September 2016
canonical SMILES
CC1CC(C(C(O1)OC2C(CC3(CO3)C(=O)C(C(C(C(OC(=O)C(C(C2C)OC4CC(C(C(O4)C)O)OC)C)C)C)O)C)C)O)N(C)C
1 reference
stated in
PubChem
PubChem CID
19822
language of work or name
English
title
oleandomycin (English)
retrieved
21 September 2016
isomeric SMILES
C[C@@H]1C[C@@H]([C@H]([C@@H](O1)O[C@H]2[C@H](C[C@@]3(CO3)C(=O)[C@@H]([C@H]([C@H]([C@H](OC(=O)[C@@H]([C@H]([C@@H]2C)O[C@H]4C[C@@H]([C@H]([C@@H](O4)C)O)OC)C)C)C)O)C)C)O)N(C)C
0 references
found in taxon
Streptomyces antibioticus
18 references
stated in
Streptomyces antibioticus contains at least three oleandomycin-resistance determinants, one of which shows similarity with proteins of the ABC-transporter superfamily.
stated in
Purification and characterization of an extracellular enzyme from Streptomyces antibioticus that converts inactive glycosylated oleandomycin into the active antibiotic
stated in
Interaction between ATP, oleandomycin and the OleB ATP-binding cassette transporter of Streptomyces antibioticus involved in oleandomycin secretion
stated in
Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus
stated in
Identification and antibacterial activity of a new oleandomycin derivative from Streptomyces antibioticus.
stated in
A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis byStreptomyces antibioticus
stated in
Characterization of the ATPase activity of the N-terminal nucleotide binding domain of an ABC transporter involved in oleandomycin secretion by Streptomyces antibioticus
stated in
Biosynthesis of oleandomycin by Streptomyces antibioticus: influence of nutritional conditions and development of resistance.
stated in
Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus
stated in
Biosynthesis of the macrolide oleandomycin by Streptomyces antibioticus. Purification and kinetic characterization of an oleandomycin glucosyltransferase
stated in
Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence.
stated in
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus
stated in
Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.
stated in
Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives
stated in
A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator
stated in
A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus
stated in
Biosynthetic studies on oleandomycin by incorporation of the chemically synthesized aglycones
stated in
Resistance to oleandomycin in Streptomyces antibioticus, the producer organism.
schematic
Oleandomycin Synthesis 2.png
1,670 × 1,077; 12 KB
0 references
Oleandomycin synthesis 1.png
1,505 × 2,061; 44 KB
0 references

Identifiers

ChemSpider ID
18672
1 reference
stated in
ChemSpider
ChemSpider ID
18672
language of work or name
English
title
(3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-12-[(2,6-dideoxy-3-O-methylhexopyranosyl)oxy]-6-hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadec-14-yl 3,4,6-trideoxy-3-(dimethylamino)hexo (English)
retrieved
21 September 2016
PubChem CID
72493
0 references
Reaxys registry number
74476
0 references
EC number
223-495-7
1 reference
stated in
ECHA Substance Infocard database
ECHA Substance Infocard ID
100.021.360
retrieved
27 December 2018
title
Oleandomycin (English)
quotation
CAS no.: 3922-90-5 (English)
E number
E704
0 references
ATC code
J01FA05
0 references
MeSH descriptor ID
D009827
subject named as
Oleandomycin
0 references
DrugBank ID
11442
1 reference
stated in
DrugBank
DrugBank ID
11442
retrieved
6 July 2021
quotation
CAS no.: 3922-90-5 (English)
title
Oleandomycin (English)
UNII
P8ZQ646136
0 references
KEGG ID
C01946
0 references
CAB ID
206354
1 reference
stated in
CAB Thesaurus
retrieved
6 April 2020
DeCS ID
27734
0 references
 
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