(Q1107734)

Gene Ontology release 2019-11-16

cellular response to diosgenin

subject has role

reactant

1 reference

Gene Ontology release 2019-11-16

chemical structure

Diosgenin.svg
512 × 289; 6 KB

0 references

image of molecular model or crystal lattice model

Diosgenina3D.png
3,494 × 1,880; 716 KB

depicts

ball-and-stick model

0 references

mass

414.313395 dalton

1 reference

(25R)-spirost-5-en-3alpha-ol

DIOSGENIN (English)

2 October 2016

2 references

inferred from InChIKey

(1S,2S,4S,5'S,6R,7S,8R,9S,12R,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

2 references

inferred from InChIKey

(1S,2S,4S,5'R,6R,7S,8R,9S,12R,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

1 reference

(1S,2S,4R,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

1 reference

(1S,2S,4R,5'R,6R,7R,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

1 reference

1 reference

(1S,2S,4S,5'R,6S,7S,8S,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

1 reference

(1S,2R,4R,5'R,6S,7R,8S,9S,12S,13R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

1 reference

chemical formula

C₂₇H₄₂O₃

1 reference

DIOSGENIN (English)

18 November 2016

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1

1 reference

DIOSGENIN (English)

18 November 2016

C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1

1 reference

DIOSGENIN (English)

18 November 2016

Trigonella corniculata

1 reference

Effect of chemical mutagens on steroidal sapogenins in Trigonella species

Trigonella balansae

1 reference

Effect of chemical mutagens on steroidal sapogenins in Trigonella species

Trigonella foenum-graecum

14 references

Variation in diosgenin levels among 10 accessions of fenugreek seeds produced in western Canada

Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds

Effect of chemical mutagens on steroidal sapogenins in Trigonella species

Hydrolysis of the steroidal glycosides in the seeds of Trigonella foenum-graecum

Economic justification of the use of fenugreek trigonella as a raw material for the production of steroid drugs

Accumulation of sterols and steroidal sapogenins in developing fenugreek pods: Possible biosynthesis in situ

Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol.

Bioproduction of diosgenin in callus cultures of Trigonella foenum-graecum L.

Distribution and changes of diosgenin during development of Trigonella foenum-graecum plants. Modulation by benzylaminopurine

Analysis of Steroidal Sapogenins from Amber Fenugreek (Trigonella foenum-graecum) by Capillary Gas Chromatography and Combined Gas Chromatography/Mass Spectrometry†

Minor Steroidal Sapogenins from Fenugreek Seeds, Trigonella foenum-graecum

Incubation Conditions for Fenugreek Whole Seed

Hybridisation for genetic improvement in the yield of diosgenin from fenugreek seed

Furostanol glycosides from Trigonella foenum-graecum seeds

Trigonella occulta

1 reference

Steroidal sapogenins from Agave cocui

Dioscorea pyrenaica

1 reference

Occurrence of diosgenin in Borderea pyrenaica, an endemic dioscoreaceae from the pyrénées

Solanum aviculare

2 references

Steroid Production by Callus and Cell Suspension Cultures of Solanum aviculare

Prospects of breeding steroid-containing species ofSolanum L. for diosgenin content

Costus igneus

1 reference

Screening for Diosgenin in Rhizomes from 3 Costus Species (C. deistellii, C. igneus, C. lucanusianus)

Costus lucanusianus

1 reference

Screening for Diosgenin in Rhizomes from 3 Costus Species (C. deistellii, C. igneus, C. lucanusianus)

Costus deistelii

1 reference

Screening for Diosgenin in Rhizomes from 3 Costus Species (C. deistellii, C. igneus, C. lucanusianus)

Costus afer

1 reference

Screening for Diosgenin in Rhizomes from 3 Costus Species (C. deistellii, C. igneus, C. lucanusianus)

Dioscorea deltoidea

8 references

High Performance Liquid Chromatographic Separation of Steroidal Sapogenins

Diosgenin formation by freely suspended and entrapped plant cell cultures of Dioscorea deltoidea.

Quantitative estimation of diosgenin in Dioscorea tubers by densitometric thin-layer chromatography

Autoclaved fungal mycelia increase diosgenin production in cell suspension cultures of Dioscorea deltoidea

Methods for Increasing Diosgenin Production by Dioscorea Cells in Suspension Cultures

Improvement of Diosgenin Yield from Dioscorea deltoidea Plant Cell Cultures by Use of a Non-Traditional Hydrolysis Method.

Timing of Diosgenin Appearance in Suspension Cultures of Dioscorea deltoidea

Diosgenin Synthesis in Shoot Cultures of Dioscorea composita

Solanum laciniatum

3 references

Determination of solasodine in cell cultures of Solanum laciniatum by high-performance liquid chromatography

Solanum-alkaloide—XLVI

Prospects of breeding steroid-containing species ofSolanum L. for diosgenin content

Borassus flabellifer

1 reference

Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer

Hellenia speciosa

6 references

Oxo acids and branched fatty acid esters from rhizomes of Costus speciosus

Homogeneous enzyme immunoassay of diosgenin and its glycosides

Distribution and Variation of Diosgenin in Different Parts of Costus speciosus

Differential diosgenin accumulation in Costus speciosus and its tissue cultures

Screening for Diosgenin in Rhizomes from 3 Costus Species (C. deistellii, C. igneus, C. lucanusianus)

Aliphatic hydroxyketones and diosgenin from Costus speciosus roots

Dioscorea collettii

1 reference

Steroidal Sapogenins in Dioscorea collettii

Dioscorea parviflora

2 references

The Dioscorea genus: a review of bioactive steroid saponins

Non-Steroidal Constituents of Dioscorea rotundata

Dracaena draco

2 references

Steroidal saponins from the bark of Dracaena draco and their cytotoxic activities.

Icogenin, a new cytotoxic steroidal saponin isolated from Dracaena draco

Smilax china

1 reference

Steroidal saponins from Smilax china and their anti-inflammatory activities

Solanum anguivi

1 reference

Diosgenin from Solanum aurantiacobaccatum de Wild

Trigonella caerulea

1 reference

22-Methyl ether of protodioscin from the seeds of Trigonella coerulea

2 references

Sapogenins ofAllium porrumL.†

Allium angulosum

1 reference

Diosgenin from Allium angulosum

Allium cernuum

1 reference

Diosgenin fromAllium nutans andA. cernuum

Allium karataviense

1 reference

Steroid saponins and sapogenins of Allium IV. Karatavigenin — A new sapogenin from Allium karataviense

Allium narcissiflorum

1 reference

Steroid saponins X. Glycosides of Allium narcissiflorum the structure of glycosides A and B

Allium nutans

2 references

Isolation of diosgenin from Solanun laciniatum

Diosgenin fromAllium nutans andA. cernuum

Allium stipitatum

1 reference

Steroids of the spirostan and furostan series from plants of the genus Allium. Structure of anzurogenin A from Allium suvorovii and A. stipitatum

Allium suworowii

1 reference

Steroids of the spirostan and furostan series from plants of the genus Allium. Structure of anzurogenin A from Allium suvorovii and A. stipitatum

Anemone raddeana

1 reference

Study on chemical constituents of rhizome of Ardisia gigantifolia

Urochloa decumbens

1 reference

Saponins and Sapogenins from Brachiaria decumbens Stapf

Urochloa eminii

1 reference

Saponins and Sapogenins from Brachiaria decumbens Stapf

Cordyline australis

2 references

Steroidal Sapogenins From Leaves of Cordyline Species

Australigenin, a New Steroidal Sapogenin from Cordyline australis Fruits

Cordyline banksii

1 reference

Steroidal Sapogenins From Leaves of Cordyline Species

Cordyline rubra

1 reference

Steroidal Sapogenins From Leaves of Cordyline Species

Cordyline stricta

1 reference

Steroidal Sapogenins From Leaves of Cordyline Species

Hellenia lacera

1 reference

Studies on chemical constituents of Rabdosia serra

Costus spiralis

1 reference

Diosgenin und Sterine ausCostus spiralis

Dendrobium fimbriatum

1 reference

Denfigenin, a diosgenin derivative from Dendrobium fimbriatum

Dioscorea balcanica

1 reference

Diosgenin and phytosterols content in five callus lines of Dioscorea balcanica

Dioscorea bernoulliana

1 reference

Studies on the Steroidal Sapogenins of the Subcellular Organelles of Dioscorea bernoulliana tubers

Dioscorea bulbifera

1 reference

Toxicity and bitterness in Australian Dioscorea bulbifera L. and Dioscorea hispida Dennst. from Thailand

Dioscorea caucasica

1 reference

Kinetics of cellular growth and diosgenin biosynthesis in Dioscorea caucasica cell suspensions, cultured in batch system

Dioscorea composita

2 references

Chemodifferentiation of diosgenin in Dioscorea composita

Spirostanic diosgenin precursors from Dioscorea composita tubers

Dioscorea dumetorum

1 reference

A Convulsant Alkaloid of Dioscorea dumetorum

Dioscorea floribunda

4 references

Quantitative estimation of diosgenin in Dioscorea tubers by densitometric thin-layer chromatography

An evaluation of a somaclone ofDioscorea floribunda Mart & Gall

Homogeneous enzyme immunoassay of diosgenin and its glycosides

Production of Diosgenin in somatic callus tissues of Dioscorea floribunda

Yam (vegetable)

1 reference

Toxicity and bitterness in Australian Dioscorea bulbifera L. and Dioscorea hispida Dennst. from Thailand

Dioscorea multiflora

1 reference

Diosgenin and Yamogenin from Dioscorea multiflora

Dioscorea nipponica

1 reference

Anti-obesity effect of Dioscorea nipponica Makino with lipase-inhibitory activity in rodents

Dioscorea olfersiana

1 reference

Steroidal prosapogenins from Dioscorea olfersiana

Dioscorea polygonoides

1 reference

Diospolysaponin A, a New Polyoxygenated Spirostanol Saponin from the Tubers of Dioscorea polygonoides.

Dioscorea sylvatica

1 reference

Quantitative estimation of diosgenin in Dioscorea tubers by densitometric thin-layer chromatography

Dracaena afromontana

1 reference

Afromontoside. A new cytotoxic principle from Dracaena afromontana

Kallstroemia pubescens

1 reference

Homogeneous enzyme immunoassay of diosgenin and its glycosides

Heteropolygonatum alte-lobatum

1 reference

Benzoquinones, a homoisoflavanone and other constitutents from Polygonatum alte-lobatum

Polygonatum stenophyllum

1 reference

Diosgenin and β-sitosterol from the hypogeal organs ofPolygonatum stenophyllum

Semiaquilegia adoxoides

2 references

Constituents from the roots of Semiaquilegia adoxoides

Constituents from the Roots of Semiaquilegia adoxoides.

Smilax excelsa

1 reference

Steroid sapogenins of Smilax excelsa

Solanum amotapense

1 reference

Steroidal Alkaloids and Sapogenins from Roots of SomeSolanumSpecies1

Solanum anomalum

1 reference

Steroidal Alkaloids and Sapogenins from Roots of SomeSolanumSpecies1

Solanum canense

1 reference

25-Isoetioline from twoSolanum species

Solanum cleistogamum

1 reference

Steroidal Alkaloids and Sapogenins from Roots of SomeSolanumSpecies1

Solanum dasyphyllum

1 reference

Constituents of Solanum dasyphyllum Fruit

Solanum fraxinifolium

1 reference

25-Isoetioline from twoSolanum species

Solanum glaucophyllum

1 reference

Steroidal Alkaloids and Sapogenins from Roots of SomeSolanumSpecies1

Solanum incanum

2 references

Diosgenin and Yamogenin from Dioscorea multiflora

STEROIDAL SAPONINS FROM SOLANUM UNGUICULATUM (A.) RICH

Solanum jasminoides

3 references

Steroids From Solanum jasminoides

Solanum jasminoides Paxt., Tissue cultures. I. Production of Steroidal Sapogenins and Glycoalkaloids

Growth and production of steroidal sapogenins and glycoalkaloids in Solanum jasminoides paxt., suspension cultures.

Solanum aculeatissimum

1 reference

Homogeneous enzyme immunoassay of diosgenin and its glycosides

Solanum panduraeforme

1 reference

(23R)-23-Hydroxysoladulcidine and related compounds from Solanum panduraeforme

Solanum virginianum

2 references

Diosgenin and beta-sitosterol: isolation from solanum xanthocarpum tissue cultures

The Isolation of Diosgenin from Solanum Xanthocarpum1

Polynesian arrowroot

1 reference

Steroidal Sapogenins from Solanum scorpioideum

Tribulus terrestris

5 references

Steroid saponins II. Glycosides of Tribulus terrestris

Homogeneous enzyme immunoassay of diosgenin and its glycosides

Steroidal saponins from Tribulus terrestris

Chemical Constituents Of Tribulus Terrestris L.

Steroidal saponins from Tribulus terrestris

Veronica gentianoides

1 reference

Steroid sapogenins of Veronica gentianoides

Allium obliquum

1 reference

Sapogenins ofAllium porrumL.†

Allium porrum

1 reference

Sapogenins ofAllium porrumL.†

Allium rotundum

1 reference

Steroidal sapogenins from Allium rotundum

Asparagus adscendens

1 reference

Steroidal saponins of Asparagus curillus

Ophiopogon intermedius

1 reference

A spirostanol glycoside from the rhizomes of Ophiopogon intermedius

Paris polyphylla

1 reference

Separation and identification of steroidal compounds with cytotoxic activity against human gastric cancer cell lines in vitro from the rhizomes of Paris polyphylla var. chinensis

Paris polyphylla var. chinensis

1 reference

Separation and identification of steroidal compounds with cytotoxic activity against human gastric cancer cell lines in vitro from the rhizomes of Paris polyphylla var. chinensis

Solanum bahamense

1 reference

Bahamgenin—a steroidal sapogenin from solanum bahamense

Solanum mammosum

2 references

Solaspigenin and neosolaspigenin, two new spirostane sapogenins from Solanum hispidum

Havanine—a steroidal alkaloid glycoside from Solanum havanense

Solanum viarum

1 reference

Solaspigenin and neosolaspigenin, two new spirostane sapogenins from Solanum hispidum

Medicago polyceratia

1 reference

Sapogenins from Trigonella polycerata

Solanum hirtum

2 references

Sapogenins from Solanum meridense

Chlorogenone and neochlorogenone from the unripe fruits of Solanum torvum

Chamaelirium luteum

1 reference

Structure and Bioactivity of Steroidal Saponins Isolated from the Roots of Chamaelirium luteum (False Unicorn)

Solanum violaceum

1 reference

Spirostanoids with 1,4-dien-3-one or 3β,7α-diol-5,6-ene moieties from Solanum violaceum.

Dioscorea zingiberensis

1 reference

Comparative Transcriptome Analysis Identifies Putative Genes Involved in Dioscin Biosynthesis in Dioscorea zingiberensis.

Solanum aurantiacobaccatum

1 reference

Diosgenin from Solanum aurantiacobaccatum de Wild

Dracaena nitens

1 reference

Dracaena nitens; A New Source of Diosgenin

Solanum aethiopicum

1 reference

Diosgenin and beta-sitosterol: isolation from solanum xanthocarpum tissue cultures

asparagus

2 references

Asparagus (Asparagus officinalis): Processing effect on nutritional and phytochemical composition of spear and hard-stem byproducts

Structural and Sensory Characterization of Bitter Tasting Steroidal Saponins from Asparagus Spears (Asparagus officinalis L.).

Solanum melongena

3 references

Glucosylation and galactosylation of diosgenin and solasodine by soluble glycosyltransferase(s) from Solanum melongena leaves

Phospholipids modulate the substrate specificity of soluble UDP-glucose:steroid glucosyltransferase from eggplant leaves

The 3-O-glucosylation of steroidal sapogenins and alkaloids in eggplant (Solanum melongena); evidence for two separate glucosyltransferases

Solanum laxum

3 references

Steroids From Solanum jasminoides

Growth and production of steroidal sapogenins and glycoalkaloids in Solanum jasminoides paxt., suspension cultures.

Solanum jasminoides Paxt., Tissue cultures. I. Production of Steroidal Sapogenins and Glycoalkaloids

Dioscorea sinoparviflora

2 references

The Dioscorea genus: a review of bioactive steroid saponins

Non-Steroidal Constituents of Dioscorea rotundata

Solanum chrysotrichum

1 reference

Chlorogenone and neochlorogenone from the unripe fruits of Solanum torvum

Solanum asperolanatum

1 reference

Chlorogenone and neochlorogenone from the unripe fruits of Solanum torvum

Dracaena hanningtonii

2 references

Steroid sapogenins from Tristagma uniflorum

Antineoplastic agents. 534. isolation and structure of sansevistatins 1 and 2 from the African Sansevieria ehrenbergii

Dalea coerulea

1 reference

22-Methyl ether of protodioscin from the seeds of Trigonella coerulea

Dioscorea saxatilis

2 references

Non-Steroidal Constituents of Dioscorea rotundata

The Dioscorea genus: a review of bioactive steroid saponins

natural product of taxon

1 reference

Diosgenin

0 references

Identifiers

InChI

InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

1 reference

DIOSGENIN (English)

18 November 2016

2 references

DIOSGENIN (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

512-04-9

2 references

Global Substance Registration System

UNII

K49P2K8WLX

diosgenin (English)

18 November 2016

https://commonchemistry.cas.org/detail?cas_rn=512-04-9

8 April 2021

1 reference

Diosgenin (English)

18 November 2016

1 reference

English

title

DIOSGENIN (English)

18 November 2016

Reaxys registry number

94582

1 reference

diosgenin (English)

2 October 2016

mapping relation type

1 reference

DISOGENIN (English)

18 November 2016

1 reference

DISOGENIN (English)

18 November 2016

1 reference

MassBank accession ID

MSBNK-NaToxAq-NA002300

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002301

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002304

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002697

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002700

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003079

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003082

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003446

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003447

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002302

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002698

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003080

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003444

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003445

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003448

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002303

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002701

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003083

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA003081

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

MSBNK-NaToxAq-NA002699

1 reference

MassBank/MassBank-data: release version 2022.06 to wikidata

4 September 2022

splash10-0kmi-0960000000-d4f931dae69f699b37b5

0 references

DSSTox substance ID

DTXSID00895074

0 references

DSSTOX compound identifier

0 references

0 references

208-134-3

1 reference

Global Substance Registration System

UNII

K49P2K8WLX

English

title

diosgenin (English)

ECHA Substance Infocard ID

18 November 2016

100.007.396

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.007.396

27 December 2018

title

(20R,25R)-spirost-5-en-3β-ol (English)

quotation

CAS no.: 512-04-9 (English)

MeSH descriptor ID

D004144

subject named as

Diosgenin

0 references

MeSH tree code

D04.210.500.247.515.500

0 references

1 reference

Global Substance Registration System

diosgenin (English)

2 October 2016

1 reference

UNII

K49P2K8WLX

diosgenin (English)

18 November 2016

0 references

1 reference

Encyclopædia Britannica Online ID

diosgenin (English)

2 October 2016

0 references

1 reference

6 April 2020

science/diosgenin

subject named as

diosgenin

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

archive URL

https://web.archive.org/web/20220125070108/https://docs.openalex.org/download-snapshot/snapshot-data-format

25 January 2022

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023