(Q14908005)

DNA (cytosine-5)-methyltransferase 1-like

1 reference

DNA (cytosine-5)-methyltransferase 1, replication foci domain, protein family

1 reference

Zinc finger, CXXC-type, protein family

1 reference

DMAP1-binding domain, protein family

1 reference

DNA methylase, C-5 cytosine-specific, active site, protein family

1 reference

DNA methylase, C-5 cytosine-specific, conserved site, protein family

1 reference

Bromo adjacent homology (BAH) domain, protein family

1 reference

methyltransferase activity

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

14 February 2019

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

DNA binding

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

zinc ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

2 references

14 February 2019

14 February 2019

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

DNA-methyltransferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

protein binding

9 references

14 February 2019

The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Replication-independent chromatin loading of Dnmt1 during G2 and M phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

DNMT1 interacts with the developmental transcriptional repressor HESX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

RNA binding

1 reference

14 February 2019

Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

DNA (cytosine-5-)-methyltransferase activity

5 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

TAS

methyl-CpG binding

1 reference

14 February 2019

Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

promoter-specific chromatin binding

ISS

protein domain specific binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

estrogen receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

histone deacetylase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

DNA binding

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

DNA (cytosine-5-)-methyltransferase activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

pericentric heterochromatin

cell component

1 reference

14 February 2019

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

replication fork

1 reference

14 February 2019

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

TAS

heterochromatin

1 reference

14 February 2019

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

nucleus

7 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

21 June 2018

Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

DNMT1 interacts with the developmental transcriptional repressor HESX1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

soma

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

nucleus

8 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

14 February 2019

Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

DNMT1 interacts with the developmental transcriptional repressor HESX1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

C-5 methylation of cytosine

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

1 reference

21 June 2018

maintenance of DNA methylation

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

negative regulation of transcription by RNA polymerase II

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

1 reference

21 June 2018

DNA methylation

DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

regulation of cell population proliferation

IGI

1 reference

14 February 2019

Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

cellular response to amino acid stimulus

IGI

1 reference

14 February 2019

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

regulation of gene expression

2 references

14 February 2019

Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

negative regulation of transcription, DNA-templated

positive regulation of DNA methylation-dependent heterochromatin assembly

ISS

Ras protein signal transduction

ISS

DNA methylation involved in embryo development

1 reference

14 February 2019

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

chromatin organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

1 reference

14 February 2019

DNA methylation on cytosine within a CG sequence

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

negative regulation of gene expression

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

DNA hypermethylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

S-adenosylmethionine metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

cellular response to transforming growth factor beta stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

negative regulation of vascular associated smooth muscle cell apoptotic process

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864

maintenance of DNA methylation

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864

Bromo adjacent homology (BAH) domain

has part(s)

1 reference

Zinc finger, CXXC-type

1 reference

DMAP1-binding domain

1 reference

DNA methylase, C-5 cytosine-specific, conserved site

1 reference

DNA methylase, C-5 cytosine-specific, active site

1 reference

DNA (cytosine-5)-methyltransferase 1, replication foci domain

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

15 May 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016