(Q14909061)

Dihydrolipoamide dehydrogenase

1 reference

FAD/NAD(P)-binding domain superfamily

1 reference

FAD/NAD(P)-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Pyridine nucleotide-disulphide oxidoreductase, class I, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

oxidoreductase activity

pyruvate dehydrogenase (NAD+) activity

2 references

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

Targeted disruption of the murine dihydrolipoamide dehydrogenase gene (Dld) results in perigastrulation lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor

IC

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

electron transfer activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

dihydrolipoyl dehydrogenase activity

5 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

Targeted disruption of the murine dihydrolipoamide dehydrogenase gene (Dld) results in perigastrulation lethality

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

dihydrolipoyl dehydrogenase activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

Targeted disruption of the murine dihydrolipoamide dehydrogenase gene (Dld) results in perigastrulation lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

flavin adenine dinucleotide binding

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

27 February 2018

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

1 reference

14 February 2019

Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

6 references

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

27 February 2018

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

oxoglutarate dehydrogenase complex

HDA

3 references

regulation of membrane potential

1 reference

14 February 2019

Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

cell redox homeostasis

1 reference

14 February 2019

1 reference

14 February 2019

Cryptic proteolytic activity of dihydrolipoamide dehydrogenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

Targeted disruption of the murine dihydrolipoamide dehydrogenase gene (Dld) results in perigastrulation lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

1 reference

14 February 2019

Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

mitochondrial electron transport, NADH to ubiquinone

IDA

1 reference

14 February 2019

Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08749

dihydrolipoamide metabolic process

IMP

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

acetyl-CoA biosynthetic process from pyruvate

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

lipoate metabolic process

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

2-oxoglutarate metabolic process

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O08749&geneProductId=UniProtKB:O08749

Pyridine nucleotide-disulphide oxidoreductase, class I, active site

histone succinylation

3 references

1 reference

Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain

1 reference

FAD/NAD(P)-binding domain

1 reference