(Q47413650)

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A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling

scientific article published on 7 November 2017

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scholarly article

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Europe PubMed Central

15 January 2018

http://europepmc.org/abstract/MED/29128334

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling (English)

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15 January 2018

http://europepmc.org/abstract/MED/29128334

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1 reference

GOA release 2020-03-11

Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

1 reference

GOA release 2020-03-11

Peroxiredoxin 5

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GOA release 2020-03-11

Pyruvate dehydrogenase E1 alpha 1

1 reference

GOA release 2020-03-11

Superoxide dismutase 1, soluble

1 reference

GOA release 2020-03-11

Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon

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GOA release 2020-03-11

Dihydrolipoamide dehydrogenase

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GOA release 2020-03-11

neurodegeneration

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based on heuristic

inferred from title

Nichollas E. Scott

17

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Sadhna Phanse

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Tiziana Alberio

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Tiziana Alberio

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Barbara Garavaglia

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Barbara Garavaglia

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Gary D Bader

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Bhanu Prasad

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James Vlasblom

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Leonard J Foster

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Leonard J Foster

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author name string

Ramy H Malty

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Hiroyuki Aoki

2

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Ashwani Kumar

3

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Shahreen Amin

5

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Qingzhou Zhang

6

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Zoran Minic

7

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Florian Goebels

8

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Gabriel Musso

9

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Zhuoran Wu

10

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Hosam Abou-Tok

11

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Michael Meyer

12

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Viktor Deineko

13

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Sandy Kassir

14

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Vishaldeep Sidhu

15

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Matthew Jessulat

16

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Xuejian Xiong

18

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Haiyuan Yu

24

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Ken Nakamura

26

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John Parkinson

27

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Mohan Babu

28

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publication date

7 November 2017

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5

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http://europepmc.org/abstract/MED/29128334

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564-577.e12

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1 reference

Europe PubMed Central

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https://europepmc.org/search?query=(METHODS:'Cytoscape')

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inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5746455/fullTextXML

based on heuristic

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Architecture of the human interactome defines protein communities and disease networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Interactome disassembly during apoptosis occurs independent of caspase cleavage

1 reference

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29 September 2018

Negative regulation of NF-κB p65 activity by serine 536 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Analysis of protein-coding genetic variation in 60,706 humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function

1 reference

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Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders

1 reference

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29 September 2018

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

1 reference

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29 September 2018

Panorama of ancient metazoan macromolecular complexes

1 reference

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Excess of rare, inherited truncating mutations in autism

1 reference

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29 September 2018

Quantitative interaction proteomics of neurodegenerative disease proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Mitochondrial dysfunction in Parkinson disease: evidence in mutant PARK2 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

ATP6AP2/(pro)renin receptor contributes to glucose metabolism via stabilizing the pyruvate dehydrogenase E1 β subunit

1 reference

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29 September 2018

The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease

1 reference

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29 September 2018

Mitochondrial targets for pharmacological intervention in human disease

1 reference

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29 September 2018

CORTECON: a temporal transcriptome analysis of in vitro human cerebral cortex development from human embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Microglial priming in neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

1 reference

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29 September 2018

Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action

1 reference

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Rotenone directly induces BV2 cell activation via the p38 MAPK pathway

1 reference

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A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.

1 reference

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1 reference

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Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle

1 reference

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1 reference

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Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae

1 reference

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A census of human soluble protein complexes

1 reference

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29 September 2018

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

PaxDb, a database of protein abundance averages across all three domains of life

1 reference

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Mitochondria: in sickness and in health

1 reference

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29 September 2018

Comparative analysis of different label-free mass spectrometry based protein abundance estimates and their correlation with RNA-Seq gene expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

1 reference

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29 September 2018

Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis

1 reference

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Network medicine: a network-based approach to human disease

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SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse

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Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

1 reference

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DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

1 reference

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NF-kappaB in the nervous system

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DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

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SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle

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Cryptic proteolytic activity of dihydrolipoamide dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746455

29 September 2018

Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

1 reference

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In vitro interactions between the two mitochondrial membrane proteins VDAC and cytochrome c oxidase

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29 September 2018

Identifiers

10.1016/J.CELS.2017.10.010

1 reference

Europe PubMed Central

15 January 2018

http://europepmc.org/abstract/MED/29128334

0 references

1 reference

Europe PubMed Central

15 January 2018

http://europepmc.org/abstract/MED/29128334

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