(Q14913588)

English

CST3

protein-coding gene in the species Homo sapiens

ARMD11
HEL-S-2
cystatin C

In more languages

Statements

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

protein-coding gene

1 reference

Ensembl Release 87

Ensembl gene ID

ENSG00000101439

Crystal structure of human cystatin C monomer.png
500 × 500; 64 KB

0 references

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

1 reference

16 March 2017

UniProt protein ID

genetic association

hereditary cystatin C amyloid angiopathy

1 reference

UniProt protein ID

13 August 2019

age related macular degeneration 11

1 reference

UniProt protein ID

13 August 2019

human chromosome 20

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

strand orientation

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

23626706

human chromosome 20

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

23608534

human chromosome 20

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

23638473

human chromosome 20

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

23619110

human chromosome 20

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

cytogenetic location

20p11.21

1 reference

15 May 2022

molecular function

amyloid-beta binding

determination method

1 reference

18 July 2017

Cystatin C modulates cerebral beta-amyloidosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

protease binding

determination method

3 references

18 July 2017

The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

endopeptidase inhibitor activity

determination method

1 reference

18 July 2017

Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

cysteine-type endopeptidase inhibitor activity

determination method

6 references

18 July 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

The salivary lipocalin von Ebner's gland protein is a cysteine proteinase inhibitor

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

protein binding

determination method

1 reference

18 July 2017

Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

extracellular region

determination method

basement membrane

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

extracellular space

determination method

4 references

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Serum cystatin C level for better assessment of glomerular filtration rate in cystic fibrosis patients treated by amikacin

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

multivesicular body

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

endoplasmic reticulum

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

endoplasmic reticulum lumen

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

nuclear membrane

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

cell projection

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

neuronal cell body

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

contractile fiber

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

perinuclear region of cytoplasm

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

extracellular exosome

determination method

4 references

18 July 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

tertiary granule lumen

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

ficolin-1-rich granule lumen

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

biological process

eye development

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to hypoxia

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

cell activation

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

apoptotic process

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

defense response

determination method

1 reference

18 July 2017

The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to oxidative stress

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

brain development

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

salivary gland development

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

embryo implantation

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

positive regulation of cell population proliferation

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

male gonad development

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to toxic substance

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to carbohydrate

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to inorganic substance

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of peptidase activity

determination method

3 references

18 July 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

18 July 2017

Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of collagen catabolic process

determination method

1 reference

18 July 2017

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of extracellular matrix disassembly

determination method

response to organic cyclic compound

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to nutrient levels

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to estradiol

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

regulation of tissue remodeling

determination method

1 reference

18 July 2017

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

cellular response to oxidative stress

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

circadian sleep/wake cycle, REM sleep

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

regulation of programmed cell death

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

neutrophil degranulation

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

post-translational protein modification

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

positive regulation of DNA replication

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of proteolysis

determination method

1 reference

18 July 2017

Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

response to axon injury

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

Sertoli cell development

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of elastin catabolic process

determination method

1 reference

18 July 2017

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of blood vessel remodeling

determination method

1 reference

18 July 2017

Cystatin C deficiency in human atherosclerosis and aortic aneurysms

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of cell death

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

cellular response to hydrogen peroxide

determination method

1 reference

18 July 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

supramolecular fiber organization

determination method

1 reference

18 July 2017

Cystatin C modulates cerebral beta-amyloidosis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

negative regulation of cysteine-type endopeptidase activity

determination method

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P01034

determination method

78

1 reference

15 May 2022

Gene Atlas image

PBB GE CST3 201360 at fs.png
732 × 530; 12 KB

0 references

1 reference

HomoloGene build68

78

1 reference

HomoloGene build68

78

1

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

nucleus accumbens

2

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

retinal pigment epithelium

3

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

right coronary artery

4

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

ascending aorta

5

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

left coronary artery

6

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

7

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

caudate nucleus

8

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

left uterine tube

9

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

10

1 reference

20 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000101439

http://identifiers.org/ncbigene/1471

1 reference

Identifiers.org

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

Ensembl gene ID

ENSG00000101439

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

Ensembl transcript ID

ENST00000398411

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

ENST00000376925

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

ENST00000398409

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000101439

HGNC gene symbol

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Online Mendelian Inheritance in Man

19 August 2019

1 reference

based on heuristic

inferred by common HGNC mappings on source and on Wikidata

15 June 2023

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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