(Q21100658)

Protein kinase-like domain superfamily

1 reference

PH-like domain superfamily

1 reference

pleckstrin homology domain, protein family

1 reference

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Rho binding domain, protein family

1 reference

Rho-associated protein kinase 1, HR1, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

image

Protein ROCK1 PDB 1s1c.png
752 × 521; 204 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

protein kinase activity

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

protein serine/threonine kinase activity

9 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

31 October 2017

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

9 references

9 May 2019

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Arachidonic acid stimulates formation of a novel complex containing nucleolin and RhoA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin β5 subunit and ROCK1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Structural insights into the interaction of ROCKI with the switch regions of RhoA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

protein serine/threonine kinase activity

IPI

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

Roles of tau protein in health and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

tau-protein kinase activity

NAS

1 reference

9 May 2019

Roles of tau protein in health and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

Rho-dependent protein serine/threonine kinase activity

NAS

1 reference

8 April 2019

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

protein serine/threonine kinase activity

10 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

secretory granule lumen

1 reference

9 May 2019

1 reference

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

cytoplasmic stress granule

negative regulation of neuron apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

leukocyte cell-cell adhesion

1 reference

9 May 2019

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

smooth muscle contraction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

intracellular signal transduction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of actin cytoskeleton organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

ephrin receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of protein binding

1 reference

9 May 2019

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of actin filament-based process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of cell motility

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of bicellular tight junction assembly

1 reference

9 May 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

vascular endothelial growth factor receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of cell adhesion

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

membrane to membrane docking

1 reference

9 May 2019

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

leukocyte tethering or rolling

1 reference

9 May 2019

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of focal adhesion assembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of angiogenesis

1 reference

9 May 2019

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of keratinocyte differentiation

1 reference

9 May 2019

Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of myosin-light-chain-phosphatase activity

I-kappaB kinase/NF-kappaB signaling

1 reference

9 May 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

cortical actin cytoskeleton organization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of establishment of endothelial barrier

actin cytoskeleton organization

1 reference

9 May 2019

Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of cytoskeleton organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

neutrophil degranulation

1 reference

9 May 2019

execution phase of apoptosis

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13464&geneProductId=UniProtKB:Q13464

protein localization to plasma membrane

G protein-coupled receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

aortic valve morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

Rho protein signal transduction

ISS

3 references

8 April 2019

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

regulation of autophagy

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

positive regulation of autophagy

1 reference

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

positive regulation of cardiac muscle hypertrophy

1 reference

9 May 2019

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

positive regulation of gene expression

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

peptidyl-serine phosphorylation

1 reference

9 May 2019

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

neuron projection development

1 reference

9 May 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

positive regulation of MAPK cascade

1 reference

9 May 2019

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of neuron differentiation

1 reference

9 May 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of membrane protein ectodomain proteolysis

1 reference

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of biomineral tissue development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of angiotensin-activated signaling pathway

ISS

1 reference

9 May 2019

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

neuron projection arborization

1 reference

9 May 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

positive regulation of amyloid-beta clearance

1 reference

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of synaptic vesicle endocytosis

1 reference

9 May 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of amyloid-beta formation

1 reference

9 May 2019

ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

negative regulation of amyloid precursor protein catabolic process

positive regulation of connective tissue replacement

1 reference

9 May 2019

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

Rho protein signal transduction

4 references

9 May 2019

Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Rho Kinase Inhibition Is Essential During In Vitro Neurogenesis and Promotes Phenotypic Rescue of Human Induced Pluripotent Stem Cell-Derived Neurons With Oligophrenin-1 Loss of Function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

peptidyl-threonine phosphorylation

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

cortical actin cytoskeleton organization

3 references

9 May 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

actomyosin structure organization

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

embryonic morphogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of stress fiber assembly

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of cell junction assembly

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

regulation of establishment of cell polarity

1 reference

9 May 2019

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13464

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5181

IUPHAR/BPS Guide to PHARMACOLOGY

17 August 2016

1 reference

Guide to Pharmacology Ligand ID

5290

17 August 2016

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3426621

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1667969

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3545065

has part(s)

serine/threonine-protein kinase, active site

1 reference

pleckstrin homology domain

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference

Rho binding domain

1 reference

AGC-kinase, C-terminal

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

Rho-associated protein kinase 1, HR1

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016