(Q24301334)

4

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Radovan Dvorsky

1

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Lars Blumenstein

2

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author name string

Ingrid R Vetter

Journal of Biological Chemistry

3

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language of work or name

English

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publication date

20 February 2004

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published in

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volume

279

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issue

8

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page(s)

7098-104

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cites work

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Regulation and functions of Rho-associated kinase

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Rho GTPases: signaling, migration, and invasion

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Rho/Rho-kinase mediated signaling in physiology and pathophysiology

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ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

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Historical review: another 50th anniversary--new periodicities in coiled coils

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Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

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Signaling to the Rho GTPases: networking with the DH domain

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Crystal structure of Rnd3/RhoE: functional implications

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Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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Rho GTPases in transformation and metastasis.

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Processing of X-ray diffraction data collected in oscillation mode

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Electron-density map interpretation

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

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Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

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Rnd proteins function as RhoA antagonists by activating p190 RhoGAP

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Coiled coils: a highly versatile protein folding motif

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The many faces of Ras: recognition of small GTP-binding proteins

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p21-activated protein kinase: a crucial component of morphological signaling?

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The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

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Structure of the TPR domain of p67phox in complex with Rac.GTP

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The GTP-binding protein Rho.

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Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein

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Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

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Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

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The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

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Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

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An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

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Structure of Cdc42 bound to the GTPase binding domain of PAK

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Rocks: multifunctional kinases in cell behaviour

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

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Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo

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Rho GTPases and their effector proteins

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Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

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Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

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Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules.

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Multiple interactions of PRK1 with RhoA. Functional assignment of the Hr1 repeat motif

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Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformation

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Characterization of RhoA-binding kinase ROKalpha implication of the pleckstrin homology domain in ROKalpha function using region-specific antibodies

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Molecular dissection of the interaction between the small G proteins Rac1 and RhoA and protein kinase C-related kinase 1 (PRK1)

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Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase

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A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

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Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo

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RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

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AMoRe: an automated package for molecular replacement

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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The guanine nucleotide-binding switch in three dimensions

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7 January 2021

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

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7 January 2021

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

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RhoE regulates actin cytoskeleton organization and cell migration.

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7 January 2021

Conformational switch and role of phosphorylation in PAK activation

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7 January 2021

RhoE binds to ROCK I and inhibits downstream signaling

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7 January 2021

Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade

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7 January 2021

Identifiers

DOI

10.1074/JBC.M311911200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

14660612

1 reference

Consolidated OpenCitations Corpus – April 2017