Wikidata

(Q21104742)

English

Phospholipase C gamma 1

mammalian protein found in Homo sapiens

  • monophosphatidylinositol phosphodiesterase
  • phospholipase C-II
  • phospholipase C, gamma 1 (formerly subtype 148)
  • PLC-148
  • PLCG1
  • 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  • phospholipase C-148
  • 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
  • Phospholipase C-gamma-1
  • phosphatidylinositol phospholipase C
  • phosphoinositidase C
  • PLC-gamma-1
  • inositoltrisphosphohydrolase
  • PLC-II
  • triphosphoinositide phosphodiesterase
  • phosphoinositide phospholipase C-gamma-1
  • phosphoinositide phospholipase C
In more languages

Statements

part of
molecular function
protein binding
determination method
IPI
44 references
retrieved
16 July 2018
stated in
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Evidence of LAT as a dual substrate for Lck and Syk in T lymphocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Novel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich region
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Interaction of phospholipase C-gamma1 with villin regulates epithelial cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
A quantitative protein interaction network for the ErbB receptors using protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Subsets of epidermal growth factor receptors during activation and endocytosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Functional interaction between c-Src and its mitotic target, Sam 68
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Fine specificity and molecular competition in SLAM family receptor signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Identification of amino acids in the N-terminal SH2 domain of phospholipase C gamma 1 important in the interaction with epidermal growth factor receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
16 July 2018
stated in
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P19174&geneProductId=UniProtKB:P19174
determination method
IPI
protein binding
determination method
IBA
IPI
45 references
retrieved
8 April 2019
stated in
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of the tyrosine kinase Tnk1 and its binding with phospholipase C-gamma1
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB
GOA
curator
UniProt
UniProt protein ID
P19174
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
A quantitative protein interaction network for the ErbB receptors using protein microarrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Functional interaction between c-Src and its mitotic target, Sam 68
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Fine specificity and molecular competition in SLAM family receptor signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Identification of amino acids in the N-terminal SH2 domain of phospholipase C gamma 1 important in the interaction with epidermal growth factor receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Formation of signal transfer complexes between stem cell and platelet-derived growth factor receptors and SH2 domain proteins in vitro
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Evidence of LAT as a dual substrate for Lck and Syk in T lymphocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Subsets of epidermal growth factor receptors during activation and endocytosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of phospholipase C-gamma1 with villin regulates epithelial cell migration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Novel Src homology 3 domain-binding motifs identified from proteomic screen of a Pro-rich region
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IPI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19174
determination method
IBA
cell component
biological process
has part(s)

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q21104742&oldid=2022922376"