(Q30009495)

21 May 2017

Competition between Grb2 and Plcγ1 for FGFR2 regulates basal phospholipase activity and invasion (English)

1 reference

21 May 2017

11

John E Ladbury

0 references

author name string

Zahra Timsah

1

1 reference

21 May 2017

Zamal Ahmed

2

1 reference

21 May 2017

Chi-Chuan Lin

3

1 reference

21 May 2017

Fernando A Melo

4

1 reference

21 May 2017

Loren J Stagg

5

1 reference

21 May 2017

Paul G Leonard

6

1 reference

21 May 2017

Prince Jeyabal

7

1 reference

21 May 2017

Jonathan Berrout

8

1 reference

21 May 2017

Roger G O'Neil

9

1 reference

21 May 2017

Mikhail Bogdanov

10

1 reference

21 May 2017

language of work or name

1 reference

19 January 2014

1 reference

full work available at URL

21 May 2017

http://eprints.whiterose.ac.uk/86703/

content deliverer

White Rose Research Online

0 references

published in

Nature Structural & Molecular Biology

1 reference

21 May 2017

21

1 reference

21 May 2017

2

1 reference

21 May 2017

180-188

1 reference

Inhibition of basal FGF receptor signaling by dimeric Grb2

21 May 2017

1 reference

Regulation of phosphoinositide-specific phospholipase C

22 May 2017

1 reference

Phospholipase Cgamma1 is required for metastasis development and progression

22 May 2017

1 reference

The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site

22 May 2017

1 reference

General and Versatile Autoinhibition of PLC Isozymes

22 May 2017

1 reference

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

22 May 2017

1 reference

Rac Regulates Its Effector Phospholipase C 2 through Interaction with a Split Pleckstrin Homology Domain

22 May 2017

1 reference

Structural insights into formation of an active signaling complex between Rac and phospholipase C gamma 2

22 May 2017

1 reference

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

22 May 2017

1 reference

Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity

22 May 2017

1 reference

Regulation of the actin cytoskeleton by PIP2 in cytokinesis

21 January 2018

1 reference

The regulation of cell motility and chemotaxis by phospholipid signaling

21 January 2018

1 reference

Phospholipase C-mediated hydrolysis of PIP2 releases ERM proteins from lymphocyte membrane

21 January 2018

1 reference

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1

21 January 2018

1 reference

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

21 January 2018

1 reference

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

21 January 2018

1 reference

A new tyrosine phosphorylation site in PLC gamma 1: the role of tyrosine 775 in immune receptor signaling

21 January 2018

1 reference

Regulation of phospholipase C isozymes by ras superfamily GTPases

21 January 2018

1 reference

Mechanism of phosphorylation-induced activation of phospholipase C-gamma isozymes

21 January 2018

1 reference

Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

21 January 2018

1 reference

Inositol phospholipids-specific phospholipase C: interaction of the gamma 1 isoform with tyrosine kinase

21 January 2018

1 reference

Phosphorylation of phospholipase Cgamma1 on tyrosine residue 783 by platelet-derived growth factor regulates reorganization of the cytoskeleton

21 January 2018

1 reference

Involvement of fibroblast growth factor receptor 2 isoform switching in mammary oncogenesis

21 January 2018

1 reference

Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform

21 January 2018

1 reference

A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiation

21 January 2018

1 reference

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

21 January 2018

1 reference

Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function

21 January 2018

1 reference

PIP2 signaling, an integrator of cell polarity and vesicle trafficking in directionally migrating cells

21 January 2018

1 reference

Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: a potential therapeutic target in colorectal cancer.

21 January 2018

1 reference

The phospholipase C isozymes and their regulation

21 January 2018

1 reference

Membrane environment exerts an important influence on rac-mediated activation of phospholipase Cγ2.

21 January 2018

1 reference

Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases

21 January 2018

1 reference

Mechanism of tyrosine phosphorylation and activation of phospholipase C-gamma 1. Tyrosine 783 phosphorylation is not sufficient for lipase activation

21 January 2018

1 reference

Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling

21 January 2018

1 reference

Determination of mass changes in phosphatidylinositol 4,5-bisphosphate and evidence for agonist-stimulated metabolism of inositol 1,4,5-trisphosphate in airway smooth muscle

21 January 2018

1 reference

Determination of content and fatty acid composition of unlabeled phosphoinositide species by thin-layer chromatography and gas chromatography

21 January 2018

1 reference

Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A.

21 January 2018

1 reference

Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system

21 January 2018

1 reference

Structure, function, and control of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

A new generation of Ca2+ indicators with greatly improved fluorescence properties

31 March 2020

1 reference

12 December 2020

Phospholipase C Isoforms, Cytoskeletal Organization, and Vascular Smooth Muscle Differentiation

1 reference

12 December 2020

Immunohistochemical detection of K-sam protein in stomach cancer

1 reference

12 December 2020

Preferential alternative splicing in cancer generates a K-sam messenger RNA with higher transforming activity

1 reference

12 December 2020

Identifiers

DOI

10.1038/NSMB.2752

1 reference

Dimensions Publication ID

21 May 2017

0 references

0 references

1 reference