(Q21112029)

English

Cereblon

mammalian protein found in Homo sapiens

protein cereblon
protein x 0001
CRBN

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

PUA-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96SW2

CULT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Yippee/Mis18/Cereblon, protein family

1 reference

based on heuristic

inferred from protein domain or family

Lon protease family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

4 references

8 April 2019

Identification of a primary target of thalidomide teratogenicity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

8 April 2019

Structural basis of lenalidomide-induced CK1α degradation by the CRL4(CRBN) ubiquitin ligase

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

8 April 2019

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

determination method

3 references

Cul4A-RING E3 ubiquitin ligase complex

determination method

1 reference

24 April 2018

Identification of a primary target of thalidomide teratogenicity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96SW2&geneProductId=UniProtKB:Q96SW2

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

biological process

negative regulation of protein homooligomerization

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

positive regulation of protein homodimerization activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

proteasome-mediated ubiquitin-dependent protein catabolic process

determination method

1 reference

8 April 2019

Identification of a primary target of thalidomide teratogenicity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

negative regulation of ion transmembrane transport

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

protein ubiquitination

determination method

3 references

8 April 2019

Identification of a primary target of thalidomide teratogenicity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96SW2

determination method

physically interacts with

object has role

reaction inhibitor

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL468

Lon, substrate-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96SW2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96SW2

Yippee/Mis18/Cereblon

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96SW2

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Encyclopædia Britannica Online ID

subject named as

cereblon

0 references

Ensembl protein ID

ENSP00000231948

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000231948

ENSP00000412499

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412499

ENSP00000392073

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000392073

ENSP00000411047

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411047

ENSP00000486286

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486286

ENSP00000491442

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000491442

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(6 entries)

bswiki CRBN
dewiki Cereblon
enwiki Cereblon
ptwiki Cereblon
ttwiki CRBN
ukwiki CRBN

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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