(Q27704179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Eric S. Fischer

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Nicolas H Thomä

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

7 April 2016

0 references

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

532

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

127-130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

7597

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

Antitumor activity of thalidomide in refractory multiple myeloma

31 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

The evolution of thalidomide and its IMiD derivatives as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Identification of a primary target of thalidomide teratogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Efficacy of lenalidomide in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Transport of thalidomide by the human intestinal caco-2 monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Cullin E3 ligases and their rewiring by viral factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Modulators of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Mechanism of auxin perception by the TIR1 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Thalidomide mimics uridine binding to an aromatic cage in cereblon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Overview of the CCP4 suite and current developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Linking Crystallographic Model and Data Quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Evaluation of comparative protein modeling by MODELLER

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Towards automated crystallographic structure refinement with phenix.refine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Inference of macromolecular assemblies from crystalline state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Multiparameter analysis of a screen for progesterone receptor ligands: comparing fluorescence lifetime and fluorescence polarization measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE16979

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

21 January 2018

1 reference

12 December 2020

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

1 reference

12 December 2020

Improvements in Solubility and Stability of Thalidomide upon Complexation with Hydroxypropyl-β-Cyclodextrin

1 reference

12 December 2020

Lenalidomide (Revlimid, CC-5013) in myelodysplastic syndromes: is it any good?

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE16979

2 references

Consolidated OpenCitations Corpus – April 2017

4256885

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26909574%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 May 2020

1027760858

0 references

4256885

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4256885