(Q34483086)

2 August 2017

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS. (English)

1 reference

2 August 2017

protein ubiquitination

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

D R Mani

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Marcus Järås

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Jan Krönke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Paul W Hollenbach

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Kyle J MacBeth

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Slater N Hurst

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Namrata D Udeshi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Philip P Chamberlain

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Hon Wah Man

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Anita K Gandhi

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Tanya Svinkina

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Rebekka K Schneider

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Marie McConkey

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Elizabeth Griffiths

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Meir Wetzler

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Lars Bullinger

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Brian E Cathers

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Steven A Carr

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Rajesh Chopra

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Benjamin L Ebert

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

language of work or name

English

0 references

publication date

1 July 2015

1 reference

2 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

7559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

page(s)

183-188

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

14 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4853910/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nature14610

0 references

cites work

Isobaric labeling-based relative quantification in shotgun proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Quantitative temporal viromics: an approach to investigate host-pathogen interaction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Casein kinase: the triple meaning of a misnomer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Large-scale identification of ubiquitination sites by mass spectrometry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Integrated proteomic analysis of post-translational modifications by serial enrichment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Casein kinase 1α regulates an MDMX intramolecular interaction to stimulate p53 binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Cancer vulnerabilities unveiled by genomic loss

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

CKIα ablation highlights a critical role for p53 in invasiveness control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Identification of a primary target of thalidomide teratogenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Ribosomopathies: human disorders of ribosome dysfunction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

CK1alpha plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Efficacy of lenalidomide in myelodysplastic syndromes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4853910

Statistical methods for assessing agreement between two methods of clinical measurement

6 July 2018

1 reference

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A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE14610

TP53 mutations in low-risk myelodysplastic syndromes with del(5q) predict disease progression.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE14610

Gene expression profiling of CD34+cells in patients with the 5q− syndrome

21 January 2018

1 reference

12 December 2020

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome

1 reference

12 December 2020

TERATOGENIC EFFECTS OF THALIDOMIDE IN RABBITS, RATS, HAMSTERS, AND MICE

1 reference

12 December 2020

Gene deletion: a new target for cancer chemotherapy

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12 December 2020

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE14610

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE14610

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26131937%20AND%20SRC:MED&resulttype=core&format=json