(Q27684738)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

19

J Wade Harper

J Wade

Harper

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kerstin Böhm

2

Kerstin

Böhm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

John R Lydeard

3

John R

Lydeard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Haidi Yang

4

Haidi

Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Michael B Stadler

5

Michael B

Stadler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Simone Cavadini

6

Simone

Cavadini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jane Nagel

7

Jane

Nagel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Fabrizio Serluca

8

Fabrizio

Serluca

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Vincent Acker

9

Vincent

Acker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Gondichatnahalli M Lingaraju

10

Gondichatnahalli M

Lingaraju

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ritesh B Tichkule

11

Ritesh B

Tichkule

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Michael Schebesta

12

Michael

Schebesta

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

William C Forrester

13

William C

Forrester

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Markus Schirle

14

Markus

Schirle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ulrich Hassiepen

15

Ulrich

Hassiepen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Johannes Ottl

16

Johannes

Ottl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Marc Hild

17

Marc

Hild

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Rohan E J Beckwith

18

Rohan E J

Beckwith

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jeremy L Jenkins

20

Jeremy L

Jenkins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Nicolas H Thomä

21

Nicolas H

Thomä

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

7 August 2014

0 references

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

512

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

7512

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

49-53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide

13 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Identification of a primary target of thalidomide teratogenicity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Mechanism of auxin perception by the TIR1 ubiquitin ligase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Thalidomide is an inhibitor of angiogenesis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Mechanisms and function of substrate recruitment by F-box proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Thalidomide-analogue biology: immunological, molecular and epigenetic targets in cancer therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Isosteric analogs of lenalidomide and pomalidomide: synthesis and biological activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

The application and biology of immunomodulatory drugs (IMiDs) in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Development, validation and application of a sensitive LC-MS/MS method for the quantification of thalidomide in human serum, cells and cell culture medium.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Transport of thalidomide by the human intestinal caco-2 monolayers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Antitumor activity of thalidomide in refractory multiple myeloma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

Further evidence for the possible role of MEIS2 in the development of cleft palate and cardiac septum.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

The evolution of thalidomide and its IMiD derivatives as anticancer agents

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423819

THALIDOMIDE IN THE TREATMENT OF LEPRA REACTIONS

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043012

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE13527

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE13527

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

1028080932

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043012%20AND%20SRC:MED&resulttype=core&format=json