(Q21126558)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

3 references

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

transferrin receptor activity

IPI

3 references

9 May 2019

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

integral component of membrane

IEA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

HFE-transferrin receptor complex

IDA

3 references

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

Co-localization of the mammalian hemochromatosis gene product (HFE) and a newly identified transferrin receptor (TfR2) in intestinal tissue and cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

external side of plasma membrane

IDA

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

positive regulation of endocytosis

biological process

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

receptor-mediated endocytosis

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

positive regulation of peptide hormone secretion

NAS

1 reference

9 May 2019

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

cellular response to iron ion

IMP

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

positive regulation of transcription by RNA polymerase II

IMP

1 reference

9 May 2019

CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

cellular iron ion homeostasis

1 reference

9 May 2019

Regulation of transferrin receptor 2 protein levels by transferrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

positive regulation of protein maturation

TAS

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

3 references

9 May 2019

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52

endocytic iron import into cell

IEA

transferrin transport

1 reference

9 May 2019

HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UP52