(Q24338877)

homeostatic iron regulator

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Hemojuvelin BMP co-receptor

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Transferrin receptor 2

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Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.

Matthias W Hentze

2

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Martina U Muckenthaler

series ordinal

3

object named as

Martina U Muckenthaler

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author name string

Flavia D'Alessio

series ordinal

1

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language of work or name

English

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publication date

November 2012

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published in

Journal of Hepatology

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volume

57

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page(s)

1052-60

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issue

5

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Huh-7: a human "hemochromatotic" cell line.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Distribution of the iron-regulating protein hepcidin in the murine central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The basal ganglia in haemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Molecular evolution of hemojuvelin and the repulsive guidance molecule family

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Two to tango: regulation of Mammalian iron metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Identification of cholesterol-regulating genes by targeted RNAi screening

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Structure of the human transferrin receptor-transferrin complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

RGM and its receptor neogenin regulate neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Iron-refractory iron deficiency anemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type I

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Expression of stimulator of Fe transport is not enhanced in Hfe knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Hereditary haemochromatosis: a case of iron accumulation in the basal ganglia associated with a parkinsonian syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Iron: a pathological mediator of Alzheimer disease?

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Diferric transferrin regulates transferrin receptor 2 protein stability

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Regulation of transferrin receptor 2 protein levels by transferrin

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Molecular mechanisms of the defective hepcidin inhibition in TMPRSS6 mutations associated with iron-refractory iron deficiency anemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Hepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Regulation of expression of murine transferrin receptor 2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

Expression of iron-related genes in human brain and brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

The role of iron in neurodegeneration: prospects for pharmacotherapy of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.JHEP.2012.06.015

7 January 2021

10.1016/J.JHEP.2012.06.015

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

593710

593710

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference